Seroprevalence of pertussis antibodies in 6-17-year-old students in Ahvaz, south-west Islamic Republic of Iran.

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Abstract

Although pertussis is a vaccine-preventable infection, vaccine-induced immunity is not lifelong and booster doses are recommended according to national disease epidemiology. The aim of this study was to evaluate pertussis-IgG levels in school-aged students in Ahvaz, south-west Islamic Republic of Iran. In a descriptive, cross-sectional study, blood samples were obtained from 640 students (382 boys and 258 girls) aged 6-17 years during 2010-2011. All students had received a full course of pertussis whole-cell vaccination at ages 2, 4, 6 and 18 months and 4-6 years. Using a Bordetella IgG ELISA kit, pertussis-IgG was detected in 301 (47.0%) students. No statistically significant differences in pertussis-IgG levels were found between girls and boys or across different age groups. The findings show that the overall level of pertussis-IgG seropositivity was unacceptable. Booster vaccination with an acellular pertussis vaccine should be considered in adolescents and/or adults in our region.

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Journal ID (iso-abbrev): East. Mediterr. Health J.

Title: Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

ISSN: 1020-3397

ISSN (Print): 1020-3397

Publication date (Electronic): Oct 20 2014

Volume: 20

Issue: 10

Affiliations

[1 ] Health Research Institute, Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran; Aboozar Children's Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.

[2 ] Health Research Institute, Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.

[3 ] Aboozar Children's Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.

[4 ] Department of Microbiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.

[5 ] Department of Epidemiology, Faculty of Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Islamic Republic of Iran.

Article

PubMed ID: 25356693

SO-VID: 30256075-b591-4e13-80e3-bd6fcf498925

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