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      Somatomedin-C/Insulin-Like Growth Factor-I as a Modulator of Growth during Childhood and Adolescence

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          Abstract

          Normal growth during childhood and adolescence is a complex process which requires the participation of a number of hormones and growth factors. Sm-C/IGF-I plays a central role in this process, with variations in both its serum concentration and the cellular responsiveness to it being important mechanisms regulating growth.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          978-3-8055-4453-5
          978-3-318-01944-5
          1663-2818
          1663-2826
          1986
          1986
          28 November 2008
          : 24
          : 2-3
          : 177-184
          Affiliations
          The Children’s Hospital of Philadelphia, Department of Endocrinology/Diabetes, Philadelphia, Penn., USA
          Article
          180557 Horm Res 1986;24:177–184
          10.1159/000180557
          3530940
          © 1986 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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          Pages: 8
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