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      Evaluation of BEBIG HDR 60Co system for non-invasive image-guided breast brachytherapy

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          Abstract

          Purpose

          HDR 60Co system has recently been developed and utilized for brachytherapy in many countries outside of the U.S. as an alternative to 192Ir. In addition, the AccuBoost ® technique has been demonstrated to be a successful non-invasive image-guided breast brachytherapy treatment option. The goal of this project is to evaluate the possibility of utilizing the BEBIG HDR 60Co system for AccuBoost treatment. These evaluations are performed with Monte Carlo (MC) simulation technique.

          Material and methods

          In this project, the MC calculated dose distributions from HDR 60Co for various breast sizes have been compared with the simulated data using an HDR 192Ir source. These calculations were performed using the MCNP5 code. The initial calculations were made with the same applicator dimensions as the ones used with the HDR 192Ir system (referred here after as standard applicator). The activity of the 60Co source was selected such that the dose at the center of the breast would be the same as the values from the 192Ir source. Then, the applicator wall-thickness for the HDR 60Co system was increased to diminish skin dose to levels received when using the HDR 192Ir system. With this geometry, dose values to the chest wall and the skin were evaluated. Finally, the impact of a conical attenuator with the modified applicator for the HDR 60Co system was analyzed.

          Results

          These investigations demonstrated that loading the 60Co sources inside the thick-walled applicators created similar dose distributions to those of the 192Ir source in the standard applicators. However, dose to the chest wall and breast skin with 60Co source was reduced using the thick-walled applicators relative to the standard applicators. The applicators with conical attenuator reduced the skin dose for both source types.

          Conclusions

          The AccuBoost treatment can be performed with the 60Co source and thick-wall applicators instead of 192Ir with standard applicators.

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          Most cited references36

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          Dosimetry of interstitial brachytherapy sources: recommendations of the AAPM Radiation Therapy Committee Task Group No. 43. American Association of Physicists in Medicine.

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            Dose calculation for photon-emitting brachytherapy sources with average energy higher than 50 keV: report of the AAPM and ESTRO.

            Recommendations of the American Association of Physicists in Medicine (AAPM) and the European Society for Radiotherapy and Oncology (ESTRO) on dose calculations for high-energy (average energy higher than 50 keV) photon-emitting brachytherapy sources are presented, including the physical characteristics of specific (192)Ir, (137)Cs, and (60)Co source models. This report has been prepared by the High Energy Brachytherapy Source Dosimetry (HEBD) Working Group. This report includes considerations in the application of the TG-43U1 formalism to high-energy photon-emitting sources with particular attention to phantom size effects, interpolation accuracy dependence on dose calculation grid size, and dosimetry parameter dependence on source active length. Consensus datasets for commercially available high-energy photon sources are provided, along with recommended methods for evaluating these datasets. Recommendations on dosimetry characterization methods, mainly using experimental procedures and Monte Carlo, are established and discussed. Also included are methodological recommendations on detector choice, detector energy response characterization and phantom materials, and measurement specification methodology. Uncertainty analyses are discussed and recommendations for high-energy sources without consensus datasets are given. Recommended consensus datasets for high-energy sources have been derived for sources that were commercially available as of January 2010. Data are presented according to the AAPM TG-43U1 formalism, with modified interpolation and extrapolation techniques of the AAPM TG-43U1S1 report for the 2D anisotropy function and radial dose function.
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              Technical note: Dosimetric study of a new Co-60 source used in brachytherapy.

              The purpose of this study is to obtain the dosimetric parameters of a new Co-60 source used in high dose rate brachytherapy and manufactured by BEBIG (Eckert & Ziegler BEBIG GmbH, Germany). The Monte Carlo method has been used to obtain the dose rate distribution in the updated TG-43U1 formalism of the American Association of Physicists in Medicine. In addition, to aid the quality control process on treatment planning systems (TPS), a two-dimensional rectangular dose rate table, coherent with the TG-43U1 dose calculation formalism, is given. These dosimetric data sets can be used as input data of the TPS calculations and to validate them.
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                Author and article information

                Journal
                J Contemp Brachytherapy
                J Contemp Brachytherapy
                JCB
                Journal of Contemporary Brachytherapy
                Termedia Publishing House
                1689-832X
                2081-2841
                30 December 2015
                December 2015
                : 7
                : 6
                : 469-478
                Affiliations
                [1 ]Radiation Medicine Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran
                [2 ]Radiation Research Center, Shiraz University, Shiraz, Iran
                [3 ]Department of Radiation Oncology, Tufts University School of Medicine, Boston, USA
                [4 ]Comprehensive Cancer Centers of Nevada, Las Vegas, USA
                Author notes
                Address for correspondence: Ali S. Meigooni, PhD, DABR, FAAPM, Comprehensive Cancer Centers of Nevada, University of Nevada Las Vegas (UNLV), 3730 S. Eastern Ave. Las Vegas, Nevada 89169, USA. phone: +1 702 343 8020. e-mail: alimeig@ 123456gmail.com
                Article
                26529
                10.5114/jcb.2015.56766
                4716133
                3046af59-63f7-45cd-9ed8-8380c2838684
                Copyright © 2015 Termedia Sp. z o. o.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

                History
                : 16 September 2015
                : 03 December 2015
                Categories
                Original Paper

                Oncology & Radiotherapy
                accuboost,brachytherapy,breast cancer,hdr
                Oncology & Radiotherapy
                accuboost, brachytherapy, breast cancer, hdr

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