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      Guaiane-Type Sesquiterpenoids from Alismatis Rhizoma and Their Anti-inflammatory Activity.

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          Abstract

          Twelve guaiane-type sesquiterpenoids, including four new ones, 10-O-methyl-orientalol A (1), 10-O-ethyl-alismoxide (2), 3β,4β-expoxy-chrysothol (3), orientalol G (4), and a new norsesquiterpenoid, orientalol H (5), were isolated from Chinese Alismatis Rhizoma, the dried rhizome of Alisma orientale. The structures of new compounds were elucidated on the basis of spectroscopic data. Moreover, the inhibition of lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW264.7 cells of all compounds was tested.

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          Author and article information

          Journal
          Chem. Pharm. Bull.
          Chemical & pharmaceutical bulletin
          Pharmaceutical Society of Japan
          1347-5223
          0009-2363
          2017
          : 65
          : 4
          Affiliations
          [1 ] Faculty of Environmental Science and Engineering, Kunming University of Science and Technology.
          Article
          10.1248/cpb.c16-00798
          28381681
          304aa23b-c12c-4f58-a772-89f317030b41
          History

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