Irreversible Cardiomyopathy due to Thyrotoxicosis

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Abstract

We report 4 adult patients with thyrotoxicosis accompanied by irreversible low-output heart failure. Each patient showed elevated plasma levels of thyroid hormone and prolonged low-output heart failure even after thyroid function returned to normal. Specimens of the right ventricular myocardium stained with anti-β myosin heavy-chain MAb showed a normal staining pattern with a predominance of the β-form. Our observations suggest that thyrotoxicosis may be one possible cause of irreversible cardiomyopathy.

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Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1994

Publication date (Print): 1994

Publication date (Electronic): 18 November 2008

Volume: 84

Issue: 4-5

Pages: 274-277

Affiliations

^aDepartment of Cardiology, Jichi Medical School, Tochigi, ^bDepartment of Third Internal Medicine, University of Tokyo, Japan

Article

Publisher ID: 176411 Other ID: Cardiology 1994;84:274–277

DOI: 10.1159/000176411

PubMed ID: 8187112

SO-VID: 309f8262-7672-4552-8cff-60d4d8196ba1

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 05 October 1993

Date accepted : 01 December 1993

Page count

Pages: 4

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