63
views
0
recommends
+1 Recommend
1 collections
    0
    shares

      To submit to this journal, click here

      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Profil épidémiologique des fibromes utérins dans la région de Sidi Bel Abbes, Algérie Translated title: Epidemiological profile of uterine fibroids in the region of Sidi Bel Abbes, Algeria

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Introduction

          Les léiomyomes ou fibromyomes plus communément dénommés fibromes, sont les tumeurs les plus répandues du tractus génital féminin. Ils affectent 20 à 25% des femmes en activité génitale. Notre étude vise à élucider la réalité de ce type de pathologie dans la région de sidi bel Abbes, nord-ouest d'Algérie.

          Méthodes

          A travers une étude rétrospective allant du 1 er janvier 2008 au 1 mai 2011 portant sur les patientes opérées pour fibrome au sein de la maternité de Sidi Bel Abbes, nous avons relevé les particularités épidémiologiques et cliniques de cette pathologie.

          Résultats

          Au total 323 cas de fibromes ont été recensés. La tranche d'âge la plus touchée varie de 40 à 44 ans dans une fourchette d'âge comprise entre 20 et 74 ans. 37.83% des patientes étaient nullipares. Une prédominance des patientes dont l'âge de la ménarche est précoce, a été retenue (60.3%). 3% des femmes ont présenté un terrain familial prédisposant. La symptomatologie était dominée par les hémorragies génitales (35%). La majorité des patientes (51.70%) présentaient un utérus polymyomateux dont la localisation des fibromes était principalement corporéale (96%), sous séreuse (43%). Le traitement était conservateur dans 71.82% des cas.

          Conclusion

          Sur la base des résultats obtenus, la mise au point d'un programme national de sensibilisation et de dépistage précoce, s'impose

          Related collections

          Most cited references17

          • Record: found
          • Abstract: found
          • Article: not found

          Uterine myomas: an overview of development, clinical features, and management.

          To review the biology and the pathophysiology of uterine myomas, focus on options for management, and emphasize principles that will render the decision-making process as logical as possible. Literature review and synthesis of the authors' experience and philosophy. Uterine myomas are the most common solid pelvic tumors in women. There is increasing evidence that they have a genetic basis and that their growth is related to genetic predisposition, hormonal influences, and various growth factors. Treatment choices are wide and include pharmacologic, surgical, and radiographically directed intervention. Most myomas can be followed serially with surveillance for development of symptoms or progressive growth. The past century has witnessed development of highly sophisticated diagnostic and therapeutic technology for myomas. The tools currently at our disposal permit greater management flexibility with safe options, which must be tailored to the individual clinical situation.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Etiology and pathogenesis of uterine leiomyomas: a review.

            Uterine leiomyomas, or fibroids, represent a major public health problem. It is believed that these tumors develop in the majority of American women and become symptomatic in one-third of these women. They are the most frequent indication for hysterectomy in the United States. Although the initiator or initiators of fibroids are unknown, several predisposing factors have been identified, including age (late reproductive years), African-American ethnicity, nulliparity, and obesity. Nonrandom cytogenetic abnormalities have been found in about 40% of tumors examined. Estrogen and progesterone are recognized as promoters of tumor growth, and the potential role of environmental estrogens has only recently been explored. Growth factors with mitogenic activity, such as transforming growth factor- (subscript)3(/subscript), basic fibroblast growth factor, epidermal growth factor, and insulin-like growth factor-I, are elevated in fibroids and may be the effectors of estrogen and progesterone promotion. These data offer clues to the etiology and pathogenesis of this common condition, which we have analyzed and summarized in this review.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Risk factors for uterine leiomyoma: a practice-based case-control study. I. African-American heritage, reproductive history, body size, and smoking.

              The authors conducted a case-control study among premenopausal women in the Baltimore, Maryland, area to examine the associations of uterine leiomyoma with ethnicity and hormone-related characteristics. Cases of uterine leiomyoma (n = 318) were surgically or sonographically first confirmed between January 1990 and June 1993. A total of 394 controls were selected from women who were visiting their gynecologist for a routine checkup. Data were collected through telephone interviews and abstraction of medical records; 77.8% of eligible cases and 78.0% of eligible controls were interviewed. Positive adjusted associations were observed between risk of uterine leiomyoma and self-described African-American ethnicity (vs. Whites: odds ratio (OR) = 9.4; 95% confidence interval (CI): 5.7, 15.7), early menarche ( 13 years: OR = 2.4; 95% CI: 1.1, 5.6), and high body mass index (upper quartile vs. lower quartile: OR = 2.3; 95% CI: 1.4, 3.8). Inverse associations were observed with use of oral contraceptives (current use vs. never use: OR = 0.2, 95% CI: 0.1, 0.6) and duration of smoking (> or =19 years vs. never: OR = 0.6; 95% CI: 0.4, 1.1). Younger ages at infertility diagnosis and at first and last childbirth were more common among cases; however, analyses of data on tumor location suggested that these associations represent predominantly consequences of uterine leiomyoma. These results suggest that development of uterine leiomyoma is associated with increased exposure to ovarian hormones. Possible reasons for the very elevated risk among African-American women need further investigation.
                Bookmark

                Author and article information

                Journal
                Pan Afr Med J
                Pan Afr Med J
                PAMJ
                The Pan African Medical Journal
                The African Field Epidemiology Network
                1937-8688
                06 May 2013
                2013
                : 15
                : 7
                Affiliations
                [1 ]Département de biologie. Faculté des sciences. Université Djillali Liabes. Sidi Bel Abbes. Algérie
                Author notes
                [& ]Corresponding author: Nourelhouda Chalal, Département de biologie, Faculté des sciences, Université Djillali Liabes, BP 89, Faubourg Larbi Ben M'hidi, 22000 Sidi Bel Abbes, Algérie
                Article
                PAMJ-15-7
                10.11604/pamj.2013.15.7.2690
                3708320
                23847704
                30acf5a3-9846-4e55-8981-eb198f130d4f
                © Nourelhouda Chalal et al.

                The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 04 April 2013
                : 23 April 2013
                Categories
                Research

                Medicine
                fibromes,étude rétrospective,particularités épidémiologiques,sidi bel abbes,fibroids,retrospective study,epidemiological features

                Comments

                Comment on this article