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      Efficacy and tolerability of aliskiren 300  mg/hydrochlorothiazide 25  mg (± amlodipine 5  mg) in hypertensive patients not controlled by candesartan 32  mg plus HCT 25  mg.

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          Abstract

          The majority of patients with essential hypertension of moderate severity (WHO grade 2) require combination therapy. We aimed to investigate whether the single-pill combination of aliskiren 300  mg and hydrochlorothiazide (HCT) 25  mg (ALIS 300/HCT 25) improves the BP reduction in hypertensive patients not adequately controlled by the free combination of candesartan 32  mg and HCT 25  mg (CAN 32 + HCT 25).

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          Author and article information

          Journal
          Curr Med Res Opin
          Current medical research and opinion
          Informa Healthcare
          1473-4877
          0300-7995
          Jan 2011
          : 27
          : 1
          Affiliations
          [1 ] Dept. of Internal Medicine, Chemnitz Hospital, Chemnitz, Germany. j.schweizer@skc.de
          Article
          10.1185/03007995.2010.537318
          21117946
          31633971-4356-4978-b50d-2ab296a32494
          History

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