Yen-Bo Su: Role: InvestigationRole: Writing – original draft
Tzu-Hao Li: Role: Project administrationRole: SoftwareRole: Validation
Chia-Chang Huang: Role: Data curationRole: Formal analysis
Hung-Cheng Tsai: Role: ConceptualizationRole: Methodology
Shiang-Fen Huang: Role: ConceptualizationRole: Validation
Yun-Cheng Hsieh: Role: InvestigationRole: Methodology
Ying-Ying Yang:
ORCID: http://orcid.org/0000-0003-2919-9853
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
ResourcesRole: SupervisionRole: Validation
Yi-Hsiang Huang: Role: ResourcesRole: Supervision
Ming-Chih Hou: Role: Project administrationRole: Supervision
Han-Chieh Lin: Role: Funding acquisitionRole: Project administrationRole: Supervision
Jordi Gracia-Sancho: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
23
April
2018
Publication date Collection: 2018
Volume: 13
Issue: 4
Electronic Location Identifier: e0194867
Affiliations
[1
]
Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
[2
]
Department of Medicine, National Yang-Ming University School of Medicine, Taipei,
Taiwan
[3
]
Division of Allergy and Immunology, Taipei Veterans General Hospital, Taipei, Taiwan
[4
]
Institute of Clinical Medicine, National Yang-Ming University School of Medicine,
Taipei, Taiwan
[5
]
Chia-Yi Branch of Taichung Veterans General Hospital, Chiayi, Taiwan
[6
]
Division of Infection, Taipei Veterans General Hospital, Taipei, Taiwan
[7
]
Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei,
Taiwan
[8
]
Division of General Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
IDIBAPS Biomedical Research Institute, SPAIN
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-17-36888
DOI: 10.1371/journal.pone.0194867
PMC ID: 5912737
PubMed ID: 29684027
SO-VID: 316a09f3-b37c-4902-af83-d884f4745d73
Copyright © © 2018 Su et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/501100001868, National Science Council;
Award ID: NSC-102-2314-B-010-036-MY3
Award Recipient
:
ORCID: http://orcid.org/0000-0003-2919-9853
Ying-Ying Yang
Funded by: Taipei Veteran General Hospital
Award ID: V106EA-007
Award Recipient
:
ORCID: http://orcid.org/0000-0003-2919-9853
Ying-Ying Yang
We especially thank Yun-Ru Wang, Fan-Yi Jhan, Che-Jui Chang and Yen-Ling Lin for their
excellent technical supports. This work was entirely supported by research grants
NSC-102-2314-B-010-036-MY3 and from the National Science Council, and V106EA-007,
VGHUST105-GI-2-2 and by the Taipei Veterans General Hospital.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Digestive System
Subject:
Gastrointestinal Tract
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Digestive System
Subject:
Gastrointestinal Tract
Subject:
Physical sciences
Subject:
Chemistry
Subject:
Chemical compounds
Subject:
Organic compounds
Subject:
Vitamins
Subject:
Vitamin D
Subject:
Physical sciences
Subject:
Chemistry
Subject:
Organic chemistry
Subject:
Organic compounds
Subject:
Vitamins
Subject:
Vitamin D
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Lipid Hormones
Subject:
Calcitriol
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Monocytes
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Signs and Symptoms
Subject:
Inflammation
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Signs and Symptoms
Subject:
Inflammation
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Molecular Development
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Hepatocytes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Liver
Subject:
Hepatocytes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Liver
Subject:
Hepatocytes
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Anatomical Pathology
Subject:
Cytopathology
Subject:
Steatosis