Idiopathic Short QT Interval:A New Clinical Syndrome?

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Abstract

In this first clinical report of an idiopathic familial persistently short QT interval (QTI), we describe three members of one family (a 17-year-old female, her 21-year-old brother, and their 51-year-old mother) demonstrating this ECG phenomenon, associated in the 17-year-old with several episodes of paroxysmal atrial fibrillation requiring electrical cardioversion. Similar ECG changes seen in an unrelated 37-year-old patient were associated with sudden cardiac death. Our report also describes other manifestations of abnormal shortening of the QTI and considers the possible arrhythmogenic potential of the short QTI.

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Author and article information

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 2000

Publication date (Print): January 2001

Publication date (Electronic): 12 January 2001

Volume: 94

Issue: 2

Pages: 99-102

Affiliations

^aMayo Physician Alliance for Clinical Trials, Mayo Clinic and Mayo Foundation, Rochester, Minn., USA, ^bCardiovascular Research and Teaching Institute, Aalst, Belgium, ^cCardiovascular Institute, University of Barcelona, Barcelona, Spain, and ^dDivision of Cardiology, Saint Louis University Health Sciences Center, Saint Louis, Mo., USA

Article

Publisher ID: 47299 Other ID: Cardiology 2000;94:99–102

DOI: 10.1159/000047299

PubMed ID: 11173780

SO-VID: 31980684-5547-4310-96fe-ca545b6c038c

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Figures: 3, References: 11, Pages: 4

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