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      Use of proteomic patterns in serum to identify ovarian cancer.

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          Abstract

          New technologies for the detection of early-stage ovarian cancer are urgently needed. Pathological changes within an organ might be reflected in proteomic patterns in serum. We developed a bioinformatics tool and used it to identify proteomic patterns in serum that distinguish neoplastic from non-neoplastic disease within the ovary.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          0140-6736
          0140-6736
          Feb 16 2002
          : 359
          : 9306
          Affiliations
          [1 ] Food and Drug Administration/National Institutes of Health Clinical Proteomics Program, Department of Therapeutic Proteins/Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA. petricoin@cber.fda.gov
          Article
          S0140-6736(02)07746-2
          10.1016/S0140-6736(02)07746-2
          11867112
          31b7bf3c-e8aa-48bb-a2fb-2598c521f81a
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