Funded by: funder-id http://dx.doi.org/10.13039/100004325, AstraZeneca;
Award ID: D589BN00039
Award Recipient
:
ORCID: http://orcid.org/0000-0002-1735-4046
Karin Provost
The funding from AstraZeneca was provided under the Investigator Initiated Grant mechanism
(D589BN00039), which was administered by the Buffalo Institute of Medical Research,
the non-profit organization associated with the VA Western New York Healthcare System
to administer non-VA grant funding. Sponsor had no role in the data collection, analysis,
or the decision to publish. Author Miyuki Smith, the lab technician, received support
in the form of a salary from the grant funding. Author Anna Miller-Larsson was a full-time
employee of AstraZeneca, and participated in the initial study design, particularly
with focus on drug solubility and ensuring equal and appropriate drug concentrations
for the experimental design. She did not have any additional role in the study design,
data collection and analysis or decision to publish the manuscript. The specific roles
of these authors are articulated in the 'author contributions' section. The funders
had no role in study design, data collection and analysis, decision to publish, or
preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Pulmonology
Subject:
Chronic Obstructive Pulmonary Disease
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Pattern Recognition Receptors
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Pattern Recognition Receptors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Pattern Recognition Receptors
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Immune Receptors
Subject:
Pattern Recognition Receptors
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Immune Receptors
Subject:
Toll-like Receptors
Subject:
Biology and Life Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Physiology
Subject:
Immune Physiology
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System
Subject:
Innate Immune System
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Developmental Biology
Subject:
Molecular Development
Subject:
Cytokines
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Macrophages
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Propionates
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Blood Cells
Subject:
White Blood Cells
Subject:
Alveolar Macrophages
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Alveolar Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Alveolar Macrophages
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Cells
Subject:
White Blood Cells
Subject:
Alveolar Macrophages
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Complement Receptors
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Complement Receptors
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Immune System Proteins
Subject:
Immune Receptors
Subject:
Complement Receptors
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Immune Receptors
Subject:
Complement Receptors