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      Demographic and socioeconomic disparities of benign cerebral meningiomas in the United States

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      Journal of Clinical Neuroscience
      Elsevier BV

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          The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.

          The 2016 World Health Organization Classification of Tumors of the Central Nervous System is both a conceptual and practical advance over its 2007 predecessor. For the first time, the WHO classification of CNS tumors uses molecular parameters in addition to histology to define many tumor entities, thus formulating a concept for how CNS tumor diagnoses should be structured in the molecular era. As such, the 2016 CNS WHO presents major restructuring of the diffuse gliomas, medulloblastomas and other embryonal tumors, and incorporates new entities that are defined by both histology and molecular features, including glioblastoma, IDH-wildtype and glioblastoma, IDH-mutant; diffuse midline glioma, H3 K27M-mutant; RELA fusion-positive ependymoma; medulloblastoma, WNT-activated and medulloblastoma, SHH-activated; and embryonal tumour with multilayered rosettes, C19MC-altered. The 2016 edition has added newly recognized neoplasms, and has deleted some entities, variants and patterns that no longer have diagnostic and/or biological relevance. Other notable changes include the addition of brain invasion as a criterion for atypical meningioma and the introduction of a soft tissue-type grading system for the now combined entity of solitary fibrous tumor / hemangiopericytoma-a departure from the manner by which other CNS tumors are graded. Overall, it is hoped that the 2016 CNS WHO will facilitate clinical, experimental and epidemiological studies that will lead to improvements in the lives of patients with brain tumors.
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            Individual Comparisons by Ranking Methods

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              Nonparametric Tests Against Trend

              Henry Mann (1945)
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                Author and article information

                Journal
                Journal of Clinical Neuroscience
                Journal of Clinical Neuroscience
                Elsevier BV
                09675868
                April 2021
                April 2021
                : 86
                : 122-128
                Article
                10.1016/j.jocn.2021.01.023
                31fb7e08-3a39-49d9-b7f1-80902c8ec3e9
                © 2021

                https://www.elsevier.com/tdm/userlicense/1.0/

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