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      Immunogenicity and safety of a 13-valent pneumococcal conjugate vaccine compared to a 23-valent pneumococcal polysaccharide vaccine in pneumococcal vaccine-naive adults.

      1 , , , , , , , , ,
      Vaccine
      13-valent pneumococcal conjugate vaccine, 23-valent polysaccharide vaccine, 7-valent pneumococcal conjugate vaccine, AE, Adult, CI, CRM197, GMR, GMT, IPD, LLOQ, LOD, OPA, PCV, PCV13, PCV7, PPSV23, Pneumococcal conjugate vaccine, Pneumonia, RCDC, SAE, adverse event, confidence interval, cross-reactive material 197, geometric mean ratio, geometric mean titer, invasive pneumococcal disease, limit of detection, lower limit of quantitation, opsonophagocytic activity, pneumococcal polysaccharide conjugate vaccine, reverse cumulative distribution curve, serious adverse event

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          Abstract

          Streptococcus pneumoniae is a major cause of morbidity and mortality among adults 50 years of age and older in the United States. Pneumococcal conjugate vaccines are efficacious against pneumococcal disease in children and may also offer advantages in adults.

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          Author and article information

          Journal
          Vaccine
          Vaccine
          1873-2518
          0264-410X
          Aug 2 2013
          : 31
          : 35
          Affiliations
          [1 ] Group Health Research Institute, Seattle, Washington, United States. jackson.l@ghc.org
          Article
          S0264-410X(13)00587-2
          10.1016/j.vaccine.2013.04.085
          23688526
          3214b16f-dc35-4a8f-8769-733a80073fd1
          Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.
          History

          13-valent pneumococcal conjugate vaccine,23-valent polysaccharide vaccine,7-valent pneumococcal conjugate vaccine,AE,Adult,CI,CRM197,GMR,GMT,IPD,LLOQ,LOD,OPA,PCV,PCV13,PCV7,PPSV23,Pneumococcal conjugate vaccine,Pneumonia,RCDC,SAE,adverse event,confidence interval,cross-reactive material 197,geometric mean ratio,geometric mean titer,invasive pneumococcal disease,limit of detection,lower limit of quantitation,opsonophagocytic activity,pneumococcal polysaccharide conjugate vaccine,reverse cumulative distribution curve,serious adverse event

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