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      Effect of short moderate intensity exercise bouts on cardiovascular function and maximal oxygen consumption in sedentary older adults

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          Abstract

          Aim

          To investigate effect of <10 min moderate intensity exercise on cardiovascular function and maximal oxygen consumption ( V ˙ O 2max) among sedentary adults.

          Methods

          We studied 53 sedentary urbanites aged ≥50 years, randomised into: (1) male (M S) and (2) female (F S) undertaking three short-duration exercise (5–10 min) daily, and (3) male (M L) and (4) female (F L) exercising 30–60 min 3–5 days weekly. Resting systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate and V ˙ O 2max were measured at baseline and 8 weekly for 24 weeks.

          Results

          At baseline, 50% M S, 61.5% M L, 53.8% F S and 53.8% F L had SBP ≥120 mm Hg, and 14.3% M S, 53.8% M L, 23.1% F S and 38.5% F L had DBP ≥80 mm Hg. At 24 weeks, where SBP remained ≥120 mm Hg, values decreased from 147±19.2 to 132.3±9.6 mm Hg (50% of M S), from 144±12.3 to 128±7.0 mm Hg (23.1% of M L), from 143.1±9.6 to 128.0±7.0 mm Hg (53.8% of F S) and from 152.3±23.7 to 129±3.7 mm Hg (30.8% of F L). For DBP ≥80 mm Hg, M S and F S percentages maintained, but values decreased from 101±15.6 to 84.5±0.7 mm Hg (M S) and 99.0±3.6 to 87.7±4.9 mm Hg (F S). In M L and F L, percentage with DBP ≥80 mm Hg dropped to 15.4% (86.1±6.5 to 82.5±3.5 mm Hg) and (91.4±5.3 to 83.5±0.71 mm Hg). V ˙ O 2max increased from 26.1±4.4 to 32.0±6.2 for M S, from 25.8±5.1 to 28.8±5.4 for M L (group differences p=0.02), from 20.2±1.8 to 22.7±2.0 for F S and from 21.2±1.9 to 24.2±2.7 for F L (groups differences p=0.38).

          Conclusion

          Accumulated moderate intensity exercise bouts of <10 min confer similar-to-better cardiovascular and V ˙ O 2max improvements compared with current recommendations among sedentary adults.

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          Most cited references34

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          Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study.

          The long-term risk for developing hypertension is best described by the lifetime risk statistic. The lifetime risk for hypertension and trends in this risk over time are unknown. To estimate the residual lifetime risk for hypertension in older US adults and to evaluate temporal trends in this risk. Community-based prospective cohort study of 1298 participants from the Framingham Heart Study who were aged 55 to 65 years and free of hypertension at baseline (1976-1998). Residual lifetime risk (lifetime cumulative incidence not adjusted for competing causes of mortality) for hypertension, defined as blood pressure of 140/90 mm Hg or greater or use of antihypertensive medications. The residual lifetime risks for developing hypertension and stage 1 high blood pressure or higher (greater-than-or-equal to 140/90 mm Hg regardless of treatment) were 90% in both 55- and 65-year-old participants. The lifetime probability of receiving antihypertensive medication was 60%. The risk for hypertension remained unchanged for women, but it was approximately 60% higher for men in the contemporary 1976-1998 period compared with an earlier 1952-1975 period. In contrast, the residual lifetime risk for stage 2 high blood pressure or higher (greater-than-or-equal to 160/100 mm Hg regardless of treatment) was considerably lower in both sexes in the recent period (35%-57% in 1952-1975 vs 35%-44% in 1976-1998), likely due to a marked increase in treatment of individuals with substantially elevated blood pressure. The residual lifetime risk for hypertension for middle-aged and elderly individuals is 90%, indicating a huge public health burden. Although the decline in lifetime risk for stage 2 high blood pressure or higher represents a major achievement, efforts should be directed at the primary prevention of hypertension.
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            Hypertension in Sub-Saharan Africa: Cross-Sectional Surveys in Four Rural and Urban Communities

            Background Cardiovascular disease (CVD) is the leading cause of adult mortality in low-income countries but data on the prevalence of cardiovascular risk factors such as hypertension are scarce, especially in sub-Saharan Africa (SSA). This study aims to assess the prevalence of hypertension and determinants of blood pressure in four SSA populations in rural Nigeria and Kenya, and urban Namibia and Tanzania. Methods and Findings We performed four cross-sectional household surveys in Kwara State, Nigeria; Nandi district, Kenya; Dar es Salaam, Tanzania and Greater Windhoek, Namibia, between 2009–2011. Representative population-based samples were drawn in Nigeria and Namibia. The Kenya and Tanzania study populations consisted of specific target groups. Within a final sample size of 5,500 households, 9,857 non-pregnant adults were eligible for analysis on hypertension. Of those, 7,568 respondents ≥18 years were included. The primary outcome measure was the prevalence of hypertension in each of the populations under study. The age-standardized prevalence of hypertension was 19.3% (95%CI:17.3–21.3) in rural Nigeria, 21.4% (19.8–23.0) in rural Kenya, 23.7% (21.3–26.2) in urban Tanzania, and 38.0% (35.9–40.1) in urban Namibia. In individuals with hypertension, the proportion of grade 2 (≥160/100 mmHg) or grade 3 hypertension (≥180/110 mmHg) ranged from 29.2% (Namibia) to 43.3% (Nigeria). Control of hypertension ranged from 2.6% in Kenya to 17.8% in Namibia. Obesity prevalence (BMI ≥30) ranged from 6.1% (Nigeria) to 17.4% (Tanzania) and together with age and gender, BMI independently predicted blood pressure level in all study populations. Diabetes prevalence ranged from 2.1% (Namibia) to 3.7% (Tanzania). Conclusion Hypertension was the most frequently observed risk factor for CVD in both urban and rural communities in SSA and will contribute to the growing burden of CVD in SSA. Low levels of control of hypertension are alarming. Strengthening of health care systems in SSA to contain the emerging epidemic of CVD is urgently needed.
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              A progressive shuttle run test to estimate maximal oxygen uptake.

              The purpose of the present study was to examine the validity of using a 20 m progressive shuttle run test to estimate maximal oxygen uptake. Running ability was described as the final level attained on the shuttle run test and as time on a 5 km run. Maximal oxygen uptake (VO2 max) was determined directly for seventy-four volunteers (36 men, 38 women) who also completed the shuttle run test. Maximal oxygen uptake values were 58.5 +/- 7.0 and 47.4 +/- 6.1 ml.kg-1.min-1 for the men and women respectively (mean +/- SD, P less than 0.01). The levels attained on the shuttle run test were 12.6 +/- 1.5 (men) and 9.6 +/- 1.8 (women; P less than 0.01). The correlation between VO2 max and shuttle level was 0.92. The correlation between VO2 max and the 5 km run was -0.94 and the correlation between both field tests was -0.96. The results of this study suggest that a progressive shuttle run test provides a valid estimate of VO2 max and indicates 5 km running potential in active men and women.
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                Author and article information

                Journal
                BMJ Open Sport Exerc Med
                BMJ Open Sport Exerc Med
                bmjosem
                bmjosem
                BMJ Open Sport — Exercise Medicine
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2055-7647
                2020
                28 February 2020
                : 6
                : 1
                : e000672
                Affiliations
                [1 ] departmentMedical Physiology , Moi University School of Medicine , Eldoret, Kenya
                [2 ] departmentMedical Physiology , University of Nairobi , Nairobi, Kenya
                Author notes
                [Correspondence to ] Dr Karani Magutah; kmagutah@ 123456yahoo.com
                Author information
                http://orcid.org/0000-0003-3105-2981
                Article
                bmjsem-2019-000672
                10.1136/bmjsem-2019-000672
                7050352
                32180993
                3233a30b-ad0d-4600-9d1a-a225b2767f04
                © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See:  http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 06 February 2020
                Funding
                Funded by: Consortium for Advanced Research Training in Africa;
                Award ID: CARTA
                Categories
                Original Research
                1506
                Custom metadata
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                cardiovascular function,maximal oxygen consumption,short and long moderate intensity exercise sessions,sedentary

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