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      Right Ventricular Aneurysm: A New Prognostic Indicator after a First Acute Myocardial Infarction

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          The prognostic implication of a right ventricular aneurysm after a first acute myocardial infarction (AMI) was assessed on a series of 137 AMI patients 12 of whom had a right ventricular aneurysm detected at radionuclide angiocardiography. The follow-up lasted 36 months. Mortality was 50 and 18.4% in patients with and without right ventricular aneurysm, respectively (p < 0.02). Groups did not differ in age, male-to-female ratio, AMI site, left ventricular ejection fraction (LVEF), peak filling rate (PFR), left ventricular size. A multivariate logistic analysis showed that only three out of ten clinical and functional variables qualified to be independent predictors of death: right ventriuclar aneurysm (odd ratio = 2.48, confidence limits = 1.21–4.98), LVEF < 52% (odd ratio = 1.91, confidence limits = 1.03–3.48), abnormal terminal P wave forces (odd ratio = 1.72, confidence limits = 1.07–2.75). The analysis of single case histories did not provide a clue to clarify the reasons accounting for the negative prognostic implication of a right ventricular aneurysm. In conclusion, a significant positive relationship between right ventricular aneurysm and mortality after AMI has been demonstrated; further study is needed to clarify the relevant mechanisms.

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          Author and article information

          S. Karger AG
          12 November 2008
          : 79
          : 2
          : 120-126
          Istituto di aClinica Medica e di bMedicina Nucleare; cCattedra di Geriatri dell’Università Cattolica del Sacro Cuore, Roma, Italia
          174869 Cardiology 1991;79:120–126
          © 1991 S. Karger AG, Basel

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          Pages: 7
          Coronary Care


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