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      Impact of Cereal Seed Sprouting on Its Nutritional and Technological Properties: A Critical Review

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          Global Prevalence of Celiac Disease: Systematic Review and Meta-analysis

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            Coeliac disease

            Coeliac disease occurs in about 1% of people in most populations. Diagnosis rates are increasing, and this seems to be due to a true rise in incidence rather than increased awareness and detection. Coeliac disease develops in genetically susceptible individuals who, in response to unknown environmental factors, develop an immune response that is subsequently triggered by the ingestion of gluten. The disease has many clinical manifestations, ranging from severe malabsorption to minimally symptomatic or non-symptomatic presentations. Diagnosis requires the presence of duodenal villous atrophy, and most patients have circulating antibodies against tissue transglutaminase; in children, European guidelines allow a diagnosis without a duodenal biopsy provided that strict symptomatic and serological criteria are met. Although a gluten-free diet is an effective treatment in most individuals, a substantial minority develop persistent or recurrent symptoms. Difficulties adhering to a gluten-free diet have led to the development of non-dietary therapies, several of which are undergoing trials in human beings.
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              Gamma Aminobutyric Acid (GABA) and Plant Responses to Stress

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                Author and article information

                Journal
                Comprehensive Reviews in Food Science and Food Safety
                Comprehensive Reviews in Food Science and Food Safety
                Wiley
                1541-4337
                1541-4337
                December 12 2018
                December 12 2018
                Affiliations
                [1 ]Laboratory of Food Chemistry and Biochemistry and Leuven Food Science and Nutrition Research Centre (LFoRCe)KU Leuven Kasteelpark Arenberg 20 B‐3001 Leuven Belgium
                [2 ]Nestlé Research Centre Route du Jorat 57 1000 Lausanne Switzerland
                [3 ]Puratos Group Industrialaan 25 B‐1702 Groot‐Bijgaarden Belgium
                [4 ]VTT Technical Research Centre of Finland Vuorimiehentie 3 02150 Espoo Finland
                [5 ]Wageningen Univ. & Research, Business unit Bioscience Droevendaalsesteeg 1 6708 PB Wageningen The Netherlands
                [6 ]Dept. of Human Biology School of Nutrition and Translational Research in Metabolism Faculty of Health, Medicine and Life SciencesMaastricht Univ. Universiteitssingel 40 6229 ER Maastricht The Netherlands
                Article
                10.1111/1541-4337.12414
                © 2018

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