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      Contribution of Four Markers of Tubular Proteinuria in Detecting Upper Urinary Tract Infections

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          Abstract

          The presence of tubular involvement, as a marker for the detection of urinary tract infection (UTI) site, was examined in 19 patients with pyelonephritis and in 15 patients with cystitis or asymptomatic bacteriuria. The urinary excretion of four markers of tubular proteinuria, β<sub>2</sub>-microglobulin (β<sub>2</sub>M), lysozyme (LZ), lactic dehydrogenase isoenzyme V (LAD-5) and N-acetyl-β D-glucosaminidase (NAG), was investigated. LAD-5 appeared particularly valuable for the early detection of upper UTI. However, the overall diagnostic accuracy appeared to be further strengthened using, besides LAD-5, one additional variable. A set of simple and noninvasive biochemical tests on urine samples can reliably help to identify the site of UTI.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1982
          1982
          03 December 2008
          : 32
          : 3
          : 234-238
          Affiliations
          aClinica Medica e bChimica e Microscopia Clinica, Facoltà di Medicina e Chirurgia, Università di Verona, Italia; cLaboratorio di Chimica Clinica, Istituti Ospedalieri di Verona, Italia
          Article
          182851 Nephron 1982;32:234–238
          10.1159/000182851
          6759951
          © 1982 S. Karger AG, Basel

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          Page count
          Pages: 5
          Categories
          Original Paper

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