Changes in ultrasound-assessed carotid intima-media thickness and plaque with a Mediterranean diet: a substudy of the PREDIMED trial.

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Abstract

The Prevención con Dieta Mediterránea (PREDIMED) trial showed that a Mediterranean diet (MedDiet) supplemented with either extra virgin olive oil or 30 g/d of mixed nuts reduced incident cardiovascular events compared with a control (low fat) diet. The mechanisms of cardiovascular protection afforded by MedDiets remain to be uncovered. We assessed the effect of both supplemented MedDiets on internal carotid intima-media thickness (ICA-IMT) and plaque height, the ultrasound features that best predict future cardiovascular events, in subjects at high cardiovascular risk.

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Journal ID (iso-abbrev): Arterioscler. Thromb. Vasc. Biol.

Title: Arteriosclerosis, thrombosis, and vascular biology

ISSN (Electronic): 1524-4636

ISSN (Print): 1079-5642

Publication date (Electronic): Feb 2014

Volume: 34

Issue: 2

Affiliations

[1 ] From the Lipid Clinic, Endocrinology and Nutrition Service, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clínic, Barcelona, Spain (A.S.-V., E.R.); Ciber Fisiopatología de la Obesidad y Nutrición (CIBERobn), Instituto de Salud Carlos III (ISCIII), Madrid, Spain (A.S.-V., E.-S.R.-M., I.N., R.d.l.T., D.C., V.R.-G., M.-C.L.-S., X.P., J.R., M.-Á.M.-G., R.E., E.R.); Department of Internal Medicine, IDIBAPS, Hospital Clinic, Barcelona, Spain (E.-S.R.-M., R.E.); Diagnostic Imaging Centre, IDIBAPS, Hospital Clínic, Barcelona, Spain (R.G., I.N.); Human Pharmacology and Clinical Neurosciences Research Group, Institut de Investigacions Mèdiques Hospital del Mar, Barcelona, Spain (R.d.l.T.); Department of Preventive Medicine, University of Valencia, Valencia, Spain (D.C.); Instituto de la Grasa, Consejo Superior de Investigaciones Cientificas, Sevilla, Spain (V.R.-G.); Department of Nutrition and Food Science, School of Pharmacy, XaRTA, INSA, University of Barcelona, Barcelona, Spain (M.-C.L.-S.); Lipids and Vascular Risk Unit, Internal Medicine, Hospital Universitario de Bellvitge, Hospitalet de Llobregat, Barcelona, Spain (X.P.); Department of Cardiology, University Hospital of Alava, Vitoria, Spain (J.R.); and Department of Preventive Medicine and Public Health, School of Medicine, University of Navarra-Clínica Universidad de Navarra, Pamplona, Spain (M.-Á.M.-G.).

Article

Publisher Item ID: ATVBAHA.113.302327

DOI: 10.1161/ATVBAHA.113.302327

PubMed ID: 24285581

SO-VID: 32aa6ca5-b456-4f43-a81f-dc415efd9547

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Keywords: carotid intima-media thickness,carotid stenosis,diet, Mediterranean,nuts,olive oil

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Keywords: carotid intima-media thickness, carotid stenosis, diet, Mediterranean, nuts, olive oil

Changes in ultrasound-assessed carotid intima-media thickness and plaque with a Mediterranean diet: a substudy of the PREDIMED trial.

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Herbal Medicines Journal (Herb Med J)

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