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      Salbutamol in paediatrics: pharmacology, prescribing and controversies.

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          Abstract

          Salbutamol has become a key drug in respiratory medicine since it was first developed by Sir David Jack et al in 1968, 5000 years after the β agonist ephedrine was first used in its raw form, as the Ma Huang herb in Chinese medicine to treat asthma. It is one of the most commonly encountered medicines in paediatric practice and the authors have found that an understanding of its pharmacology in clinical practice is incredibly helpful. In this article, we discuss its pharmacology and pharmacodynamics, practical prescribing points and some unresolved issues surrounding its use, which should serve to provide an essential working knowledge for the busy paediatrician.

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          Author and article information

          Journal
          Arch Dis Child Educ Pract Ed
          Archives of disease in childhood. Education and practice edition
          BMJ
          1743-0593
          1743-0585
          Aug 2016
          : 101
          : 4
          Affiliations
          [1 ] Sheffield Hand Centre, Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital, Sheffield, South Yorkshire, UK.
          [2 ] Department of Respiratory Paediatrics, University Hospitals of North Midlands, Staffordshire, UK.
          Article
          archdischild-2014-307285
          10.1136/archdischild-2014-307285
          27059284
          32b59c62-8eaa-4193-8071-f6e84d82b743
          History

          Accident & Emergency,General Paediatrics,Genetics,Pharmacology,Respiratory

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