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      Different Patterns of Hemodynamic Abnormalities in Patients with Ischemic Heart Disease Compared with Patients with Congestive Cardiomyopathy

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          Abstract

          48 patients with chest pain or unexplained heart failure were examined with exercise test, systolic time intervals, apexcardiogram and left- and right-sided heart catheterization including coronary arteriography. The 23 patients with ischemic heart disease (IHD) and 19 patients with congestive cardiomyopathy (COCM) could as groups be separated by several of the parameters. Two major patterns of change were present when using the whole range of parameters, probably reflecting that the heart and circulation had compensated for left ventricular dysfunction in different ways in IHD and COCM. Comparing patients with the same ejection fraction (EF), preejection-period index (PEPI) pre-ejection-period/left ventricular ejection time (PEP/LVET) and systolic blood pressure/left ventricular end systolic volume index (SBP/LVESVI), were all more abnormal in patients with COCM than with IHD at most EF levels. The best separation between the diseases was obtained using exercise capacity in combination with PEP/LVET. The correlations between invasive and noninvasive parameters underlined that no single parameter can satisfactorily characterize the circulatory function in patients with individual differences in preload, afterload, pulse rate, cardiac volumes, compliance and contractility. No or poor correlations were found between exercise capacity and the different function parameters used.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1986
          1986
          11 November 2008
          : 73
          : 3
          : 121-131
          Affiliations
          Cardiovascular Laboratory of Medical Department B, and Department of Diagnostic Radiology, Cardiovascular Section, Rigshospitalet, University Hospital, Copenhagen, Denmark
          Article
          173995 Cardiology 1986;73:121–131
          10.1159/000173995
          3719597
          © 1986 S. Karger AG, Basel

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          Page count
          Pages: 11
          Categories
          Original Paper

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