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      Comparison of hydroxyethyl starch colloids with crystalloids for surgical patients: A systematic review and meta-analysis.

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          Abstract

          Fluid therapy is one of the most ubiquitous medical therapeutic interventions. There is a debate over whether colloids or crystalloids are better for fluid resuscitation. Recent large trials and meta-analyses suggest no mortality benefit and possible harm with hydroxyethyl starch (HES) use. However, these trials were conducted in critically ill and septic patients and their applicability to perioperative patients has been challenged.

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          Author and article information

          Journal
          Eur J Anaesthesiol
          European journal of anaesthesiology
          Ovid Technologies (Wolters Kluwer Health)
          1365-2346
          0265-0215
          Jan 2016
          : 33
          : 1
          Affiliations
          [1 ] From the Department of Anaesthesia, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban (MR), Department of Anaesthesia, Grey's Hospital, Pietermaritzburg (CGM), Perioperative Research Group, Department of Anaesthesia, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban (BMB), Perioperative Research Group, Department of Anaesthesia, Grey's Hospital, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Pietermaritzburg, South Africa, and Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio, USA (RNR).
          Article
          10.1097/EJA.0000000000000328
          26351826
          34e4ad78-22fa-40fb-831d-89d481d66fb0
          History

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