12
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      Hemodynamic effects of a novel hypotensive peptide, human adrenomedullin, in rats

      , , , , , ,
      European Journal of Pharmacology
      Elsevier BV

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The hemodynamic effects of human adrenomedullin were investigated in anesthetized Wistar rats. Intravenous administration of adrenomedullin (1.0 nmol/kg) caused a rapid and marked reduction in mean blood pressure associated with a decrease in total peripheral resistance. This reduction in mean blood pressure was closely correlated with the decrease in total peripheral resistance. These findings indicate that human adrenomedullin is a potent vasodilator and may have some role in the regulation of blood pressure.

          Related collections

          Author and article information

          Journal
          European Journal of Pharmacology
          European Journal of Pharmacology
          Elsevier BV
          00142999
          September 1993
          September 1993
          : 241
          : 2-3
          : 271-273
          Article
          10.1016/0014-2999(93)90214-3
          8243562
          357fa510-ea3f-4b80-8cc6-0ff0ff0338a8
          © 1993

          https://www.elsevier.com/tdm/userlicense/1.0/

          History

          Comments

          Comment on this article