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      A Randomized, Controlled Trial of the Pan-PPAR Agonist Lanifibranor in NASH

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          Abstract

          <p class="first" id="d2695949e266">Management of nonalcoholic steatohepatitis (NASH) is an unmet clinical need. Lanifibranor is a pan-PPAR (peroxisome proliferator-activated receptor) agonist that modulates key metabolic, inflammatory, and fibrogenic pathways in the pathogenesis of NASH. </p>

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          Author and article information

          Contributors
          Sven M. Francque: (View ORCID Profile)
          Nicolas Lanthier: (View ORCID Profile)
          Jörn M. Schattenberg: (View ORCID Profile)
          Journal
          Title: New England Journal of Medicine
          Abbreviated Title: N Engl J Med
          Publisher: Massachusetts Medical Society
          ISSN (Print): 0028-4793
          ISSN (Electronic): 1533-4406
          Publication date Created: October 21 2021
          Publication date (Print): October 21 2021
          Volume: 385
          Issue: 17
          Pages: 1547-1558
          Affiliations
          [1 ]From Antwerp University Hospital and the Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (S.M.F., L.V.), and Service d’Hépato-Gastroentérologie, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (N.L.) and Cliniques Universitaires de Bruxelles–Hôpital Erasme, Université Libre de Bruxelles (C.M.), Brussels — all in Belgium; the Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom (P....
          Article
          DOI: 10.1056/NEJMoa2036205
          PubMed ID: 34670042
          SO-VID: 35f36717-2c50-45ef-bb95-0a175da76140
          Copyright © © 2021
          License:

          http://www.nejmgroup.org/legal/terms-of-use.htm

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