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      Chronic bowel obstruction from colonic stenosis in early infancy-A report of two cases

      case-report

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          Abstract

          Bowel obstruction in early infancy may result from a variety of congenital anomalies involving parts of the small and large bowel. However, in infancy, chronic bowel obstructions from congenital or acquired stenosis of the colon are rare and can cause diagnostic quandary. We present two cases of an eleven-week old male and a nine-week old male with massive abdominal distension and features of chronic bowel obstruction dating from neonatal period. In the first case investigations were inconclusive and laparotomy revealed isolated stenosis of the ascending colon. In the second case colonic stenosis was suspected preoperatively and a barium enema done showed multiple colonic stenosis confirming our working diagnosis. The diagnostic dilemmas encountered in managing the first patient are discussed to highlight the need for high index of suspicion of this condition in infants with chronic constipation. The way experience in managing the first case influenced diagnosis of the second case is also highlighted.

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          Most cited references13

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          Intestinal obstruction in neonatal/pediatric surgery.

          Intestinal obstruction in the newborn infant and older child may be due to a variety of conditions, including atresia and stenosis, annular pancreas, malrotation, duplication cyst, meconium ileus, meconium plug syndrome and neonatal small left colon syndrome, Hirschsprung's disease, neoplasia, trauma, and other rarer causes. The mode of presentation can be acute or more chronic with systemic upset due to shock. Neonates, more so than older children, with unrecognized intestinal obstruction deteriorate rapidly, show an increase of associated morbidity and mortality and appropriate surgical treatment becomes more hazardous. Early diagnosis depends largely on the prompt detection of obstructive manifestations by the clinician and the subsequent accurate interpretation of radiographic findings and other investigations, leading to definitive treatment, which should always be preceded by appropriate resuscitation/preparation of the infant/child. Management of intestinal obstruction will almost always be surgical, apart from some notable exceptions and all are discussed in more detail. With the advent of pediatric and neonatal intensive care and multidisciplinary care, the morbidity and mortality of cases of intestinal obstruction reported in current series is generally extremely low and mainly determined by the coexistence of other major congenital anomalies (eg, cardiac), delays in diagnosis and treatment or coexisting medical conditions. Newer treatments and future developments may reduce the residual mortality in such cases as ultrashort-bowel syndrome.
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            Intestinal Strictures Post-Necrotising Enterocolitis: Clinical Profile and Risk Factors

            Background: Intestinal stricture is an important complication of necrotising enterocolitis (NEC). We aimed to describe clinical profile and identify the risk factors for post-NEC intestinal strictures. Method: A retrospective study of infants with NEC over 10 year period. Results: Of the 61 infants with NEC, 18 (29.5%) developed intestinal strictures. Leucocytosis and longer length of bowel resection during acute stage of NEC was associated with a later diagnosis of intestinal stricture. Infants with NEC who did not develop stricture had non-specific intestinal dilatation on abdominal x-ray during acute NEC. Intestinal strictures were diagnosed at a median interval of 34 days after NEC. Majority of strictures (67%) occurred in the colon. A significant proportion (77%) of infants with intestinal stricture had associated co-morbidities. No mortality occurred in infants with intestinal strictures. Conclusion: The incidence of post-NEC intestinal stricture is high but development of stricture is difficult to predict. Leucocytosis during NEC and length of bowel resected at surgery may be associated with development of post-NEC intestinal stricture. A substantial number of infants with post-NEC intestinal stricture fail to thrive, have co-morbidities and need prolonged hospitalisation.
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              Colonic Atresia and Stenosis: Our Experience

              Background: Colonic atresia and stenosis are rare entities. On average 1 case per year of colonic atresia is being seen in most of pediatric surgical centers and to date less than 10 cases of colonic stenosis have been reported. Material and Methods: The medical record of patients of colonic atresia and stenosis managed during March 2006 to March 2010 was reviewed. Results: A total of 15 patients of colonic atresia (11) and stenosis (4) were the study population. Four were ascending colon atresia, 2 at hepatic flexure and transverse colon each, and 1 at sigmoid colon. Two patients had multiple colonic atresias. One patient of ascending colon atresia also had pyloric atresia. In colonic stenosis population (two congenital and two secondary to necrotizing enterocolitis), two were transverse colon stenosis and two were sigmoid colon stenosis. The preoperative diagnosis was distal small bowel atresia in 11 patients. Colonic atresias were managed by colocolic anastomosis with covering ileostomy in 8 patients. The remaining 3 patients were managed by exteriorizing both ends of atresia. Colonic stenosis cases were managed by primary colocolic anastomosis in 1 patient and colocolic anastomosis under covering ileostomy in 3 patients. Three patients of colonic atresia succumbed postoperatively. Conclusion: Colonic atresia and stenosis are rare entities. Associated alimentary tract malformations may result poor prognosis. Colonic atresia can safely be managed by colocolic anastomosis with covering ileostomy.
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                Author and article information

                Journal
                Malawi Med J
                Malawi Med J
                Malawi Medical Journal
                The Medical Association Of Malawi (Malawi )
                1995-7262
                1995-7270
                March 2019
                : 31
                : 1
                : 82-85
                Affiliations
                Sub-Department of Paediatric Surgery, College of Medicine, University of Nigeria
                Author notes
                Article
                10.4314/mmj.v31i1.14
                6526347
                361e792e-4de4-4756-8f01-0228de552fbc
                © 2019 The College of Medicine and the Medical Association of Malawi.

                This work is licensed under the Creative Commons Attribution 4.0 International License. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/)

                History
                : 25 May 2018
                : 10 December 2018
                : 31 December 2018
                Categories
                Case Report

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