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      Evaluation of Sodium Hyaluronate Lubricating Drops Used before Insertion of Contact Lenses on Symptomatology, Severity, and Intensity of Ocular Dryness

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      Author(s): * ,
      Publication date (Electronic):
      Journal: ISRN Ophthalmology
      Publisher: International Scholarly Research Network

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          Abstract

          Purpose. This study aimed to evaluate outcomes from the use of a sodium hyaluronate (SH)-based comfort drop, instilled before the insertion of contact lenses, in a population of symptomatic contact lens wearers. Methods. This was a cross-over, open-label, multi-sites study. Subjects were fitted with silicone hydrogel lenses and followed for two months. Before insertion of the lenses, SH drops was instilled in the lens for half of the group. The other half did the same on the second month. Objectives and subjective outcomes were measured and compared before from baseline with the ones collected after usage of SH drops.

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          Most cited references27

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          A patient questionnaire approach to estimating the prevalence of dry eye symptoms in patients presenting to optometric practices across Canada.

          D Fonn, David Doughty, Marion K. Gordon … (1997)
          To collect questionnaire data from patients in a large clinical population that would allow for an estimate of the prevalence of self-reported symptoms of dry eyes. A 13-point questionnaire (The Canada Dry Eye Epidemiology Study, CANDEES) was mailed to all optometric practices in Canada in October 1994, with the request that it be completed by 30 successive nonselected patients. Four hundred fifty sets of questionnaires (total, 13,517) were analyzed (a 15.7% return rate) from patients aged from 80 years; 55% were in the 21- to 50-year age group; 60.7% were female; and 24.3% were contact lens wearers. A total of 28.7% reported dry eye symptoms, of whom 24.2% reported concurrent dry mouth, 24.5% had worse symptoms in the morning, 30.3% reported concurrent lid problems, and 35.7% reported a history of allergies. Of the 3716 patients reporting symptoms, 62 (1.6%) were in the "severe" category and 290 (7.8%) were in the "constant but moderate" category. Contact lens wear, concurrent allergies, dry mouth, lid problems, or use of medications increased the chance of a patient reporting dry eye symptoms. The prevalence of patients reporting any level of symptoms of dry eyes was approximately 1 in 4; severe symptoms were reported by 1 in 225 patients.
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            A multi-centre study of lapsed contact lens wearers.

            Graeme Young, Jane Veys, Nicola Pritchard … (2002)
            Discontinuation from contact lens wear has been identified as a contributing factor in the lack of growth of contact lens use in Europe. The purpose of this study was to determine the proportion of lapsed contact lens wearers that can be refitted successfully with contact lenses and to evaluate the reasons for discontinuation from contact lens wear.
            Article 0 comments Cited 41 times – based on 0 reviews     Review now
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              Prevalence of ocular surface symptoms, signs, and uncomfortable hours of wear in contact lens wearers: the effect of refitting with daily-wear silicone hydrogel lenses (senofilcon a).

              Graeme Young, Michael C. Riley, Robin Chalmers (2006)
              Many soft contact lens wearers have symptoms or signs that compromise successful lens wear. This study estimated the prevalence of problems in current wearers of soft contact lenses and tested the effect of refitting patients with senofilcon A silicone hydrogel lenses (ACUVUE Oasys). Prevalence was estimated from 1,092 current lens wearers for frequent or constant discomfort or dryness, at least 2 hours of uncomfortable wear, at least grade 2 limbal or bulbar hyperemia (0-4), or at least grade 3 corneal staining (0-15). In the second part of the study, 112 of the 564 wearers classified as problem patients were refitted with senofilcon A lenses and reassessed 2 weeks later. Fifty-two percent (564 of 1,092) had some qualifying criteria, with dryness reported by 23%, discomfort by 13%, and at least 2 hours of uncomfortable wear by 27%. Six percent of subjects had qualifying limbal hyperemia; 10% had bulbar hyperemia; and 12% had corneal staining. After refitting 112 problem patients, 75% had less dryness; 88% had better comfort (P<0.0001 each); and 76% had fewer uncomfortable hours of wear (P=0.004). Although the average wearing time was unchanged, comfortable wearing time increased significantly (10.4 to 11.6 hours) (P=0.004). All (35 of 35) eyes with qualifying limbal hyperemia before the refit also improved (P<0.0001), as did 80% (40 of 50) of those with bulbar hyperemia (P<0.0001) and 76% (26 of 34) of those with corneal staining (P=0.005). Most soft lens wearers encounter clinically significant signs or symptoms with their current contact lenses. Refitting with new-generation silicone hydrogel lenses (senofilcon A) can alleviate some of these common problems.
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                Author and article information

                Journal
                Journal ID (nlm-ta): ISRN Ophthalmol
                Journal ID (iso-abbrev): ISRN Ophthalmol
                Journal ID (publisher-id): ISRN.OPHTHALMOLOGY
                Title: ISRN Ophthalmology
                Publisher: International Scholarly Research Network
                ISSN (Print): 2090-5688
                ISSN (Electronic): 2090-5696
                Publication date Collection: 2012
                Publication date (Electronic): 2 September 2012
                Volume: 2012
                Electronic Location Identifier: 762784
                Affiliations
                École d'Optométrie, Université de Montréal, 3744 Jean-Brillant, Montréal, QC, Canada H3T 1P1
                Author notes

                Academic Editors: A. Barak, J. S. Lai, and I. J. Wang

                Article
                DOI: 10.5402/2012/762784
                PMC ID: 3914261
                SO-VID: 3632d8a2-adec-421f-91da-26c95c726b92
                Copyright © Copyright © 2012 L. Michaud and B. Frenette.
                License:

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 23 May 2012
                Date accepted : 19 July 2012
                Categories
                Subject: Clinical Study

                Data availability:

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