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      The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

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          Abstract

          The morphologic and molecular phenotype of breast cancers may help identify patients who are likely to carry germline mutations in BRCA1 and BRCA2. This study evaluates the immunohistochemical profiles of tumors arising in patients with mutations in these genes.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          0732-183X
          0732-183X
          May 01 2002
          : 20
          : 9
          Affiliations
          [1 ] Breakthrough Toby Robins Breast Cancer Research Centre, Institute of Cancer Research and the Royal Marsden Hospital, London, United Kingdom. lakhani@icr.ac.uk
          Article
          10.1200/JCO.2002.09.023
          11981002
          365ff8d5-b041-4f06-987d-026f91675d3f
          History

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