Patient reported outcome measures (PROMs) following forward planned field-in field IMRT: results from the Cambridge Breast IMRT trial.

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Abstract

The use of intensity-modulated radiotherapy (IMRT) in breast cancer reduces clinician-assessed breast tissue toxicity including fibrosis, telangectasia and sub-optimal cosmesis. Patient reported outcome measures (PROMs) are also important as they provide the patient's perspective. This longitudinal study reports on (a) the effect of forward planned field-in-field IMRT (∼simple IMRT) on PROMs compared to standard RT at 5 years after RT, (b) factors affecting PROMs at 5years after RT and (c) the trend of PROMs over 5 years of follow up.

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Journal

Journal ID (iso-abbrev): Radiother Oncol

Title: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Publisher: Elsevier BV

ISSN (Electronic): 1879-0887

ISSN (Print): 0167-8140

Publication date (Electronic): May 2014

Volume: 111

Issue: 2

Affiliations

[1 ] Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, UK; Department of Oncology, Colchester Hospital University NHS Foundation Trust, Essex, UK. Electronic address: drmukesh1980@doctors.net.uk.

[2 ] Cambridge Cancer Trials Centre, Cambridge Clinical Trials Unit - Cancer Theme, Cambridge University Hospitals NHS Foundation Trust, Medical Research Council, Biostatistics Unit Hub for Trials Methodology, UK.

[3 ] Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, UK.

[4 ] Cancer Research-UK Centre for Genetic Epidemiology & Dept of Oncology, University of Cambridge, Strangeways Research Laboratory, UK.

[5 ] Oncology Centre, Cambridge University Hospitals NHS Foundation Trust, UK; Cancer Research-UK Centre for Genetic Epidemiology & Dept of Oncology, University of Cambridge, Strangeways Research Laboratory, UK.

[6 ] University of Cambridge, Department of Oncology, Oncology Centre, Addenbrooke's Hospital, UK.

[7 ] Faculty of Health, Social Care & Education, Anglia Ruskin University, Cambridge, UK.

Article

Publisher Item ID: S0167-8140(14)00121-2

DOI: 10.1016/j.radonc.2014.02.016

PubMed ID: 24746570

SO-VID: 36d4ff60-0cf6-4145-8a16-93919c7ce6e0

History

Keywords: Breast cancer,IMRT,Patient reported outcome measures

Data availability:

Keywords: Breast cancer, IMRT, Patient reported outcome measures

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