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      Guideline for the production of multicentre physiological reference values using the same measurement system. A proposal of the Catalan Association for Clinical Laboratory Sciences.

      Clinical chemistry and laboratory medicine : CCLM / FESCC
      Clinical Chemistry Tests, standards, Clinical Laboratory Techniques, Humans, Multicenter Studies as Topic, Reference Standards, Reference Values, Research Design

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          Abstract

          This article is intended as a guide for the production of biological reference values of healthy people (physiological reference values) by several clinical laboratories using the same measurement system. This guide is a proposal from the Catalan Association of Clinical Laboratory Sciences to be applied worldwide at a regional level. This guide makes it possible for all clinical laboratories in a region using the same measurement system to adopt the same physiological reference limits. The model presented here is based on the assumption that the production of physiological reference values is a professional task that should be shared by both clinical laboratories and the in vitro diagnostics industry.

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