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Abstract
This review covers three areas in endometrial tumor pathology: International Federation
of Gynecology and Obstetrics (FIGO) staging, the use of frozen section, and Lynch
syndrome. The section on FIGO staging will emphasize problems that practicing pathologists
often confront, such as measuring the depth of myometrial invasion, assessing for
the presence of cervical stromal invasion, detecting low-volume lymph node metastases,
and recognizing synchronous endometrial and ovarian tumors and artifacts. The frozen
section portion of this review will focus on the performance characteristics of intraoperative
examination of the uterus to determine tumor grade and depth of myometrial invasion,
including suggestions for alternative methods. The last portion of this review will
provide an overview of Lynch syndrome and a discussion of the rationale and methods
of screening for Lynch syndrome.