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Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
Timothy J Ley ,
Christopher Miller ,
Li Ding ,
Benjamin J Raphael ,
Andrew J Mungall ,
A Gordon Robertson ,
Katherine Hoadley ,
Timothy J Triche ,
Peter W Laird ,
Jack D Baty ,
Lucinda L Fulton ,
Robert Fulton ,
Sharon E Heath ,
Joelle Kalicki-Veizer ,
Cyriac Kandoth ,
Jeffery M Klco ,
Daniel C Koboldt ,
Krishna-Latha Kanchi ,
Shashikant Kulkarni ,
Tamara L Lamprecht ,
David E Larson ,
Ling Lin ,
Charles Lu ,
Michael D McLellan ,
Joshua F McMichael ,
Jacqueline Payton ,
Heather Schmidt ,
David H Spencer ,
Michael H Tomasson ,
John W Wallis ,
Lukas D Wartman ,
Mark A Watson ,
John Welch ,
Michael C Wendl ,
Adrian Ally ,
Miruna Balasundaram ,
Inanc Birol ,
Yaron Butterfield ,
Readman Chiu ,
Andy Chu ,
Eric Chuah ,
Hye-Jung Chun ,
Richard Corbett ,
Noreen Dhalla ,
Ranabir Guin ,
An He ,
Carrie Hirst ,
Martin Hirst ,
Robert A Holt ,
Steven Jones ,
Aly Karsan ,
Darlene Lee ,
Haiyan I Li ,
Marco A Marra ,
Michael Mayo ,
Richard A Moore ,
Karen Mungall ,
Jeremy Parker ,
Erin Pleasance ,
Patrick Plettner ,
Jacquie Schein ,
Dominik Stoll ,
Lucas Swanson ,
Angela Tam ,
Nina Thiessen ,
Richard Varhol ,
Natasja Wye ,
Yongjun Zhao ,
Stacey Gabriel ,
Gad Getz ,
Carrie Sougnez ,
Lihua Zou ,
Mark D M Leiserson ,
Fabio Vandin ,
Hsin-Ta Wu ,
Frederick Applebaum ,
Stephen B Baylin ,
Rehan Akbani ,
Bradley M Broom ,
Ken Chen ,
Thomas C Motter ,
Khanh Nguyen ,
John N Weinstein ,
Nianziang Zhang ,
Martin L Ferguson ,
Christopher Adams ,
Aaron Black ,
Jay Bowen ,
Julie Gastier-Foster ,
Thomas Grossman ,
Tara Lichtenberg ,
Lisa Wise ,
Tanja Davidsen ,
John A Demchok ,
Kenna R Mills Shaw ,
Margi Sheth ,
Heidi J Sofia ,
Liming Yang ,
James R Downing ,
Greg Eley
May 30 2013
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Abstract
Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear.