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      Estrogen and adult neurogenesis in the amygdala and hypothalamus.

      Brain Research Reviews
      Amygdala, cytology, physiology, Animals, Cell Proliferation, Estrogens, Female, Humans, Hypothalamus, Male, Neurons, Social Environment

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          Abstract

          In mammals, adult neurogenesis has been extensively studied in the dentate gyrus of the hippocampus and subventricular zone. However, newly proliferated neurons have also been documented in other brain regions, including the amygdala and hypothalamus. In this review, we will examine the evidence for new neurons in the adult amygdala and hypothalamus and then discuss how environmental influences can alter cell proliferation. As some of these environmental effects may be attributed to changes in the levels of circulating hormones, we will provide evidence for estrogen-mediated cell proliferation among different species and between sexes. Finally, we will review recent data suggesting that new neurons may become functionally significant in adulthood.

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          Author and article information

          Journal
          17764748
          2373759
          10.1016/j.brainresrev.2007.06.011

          Chemistry
          Amygdala,cytology,physiology,Animals,Cell Proliferation,Estrogens,Female,Humans,Hypothalamus,Male,Neurons,Social Environment

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