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Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant.

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      Abstract

      5-Fluorouracil (5-FU) has been well described for a failing trabeculectomy bleb, but not for aqueous shunts. We sought to determine whether subconjunctival 5-FU prolongs the intraocular pressure (IOP) efficacy of Ahmed shunts.

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      Affiliations
      [1 ] Loma Linda VA, Loma Linda University, 11201 Benton St, Loma, Linda, CA, 92357, USA.
      [2 ] Center for Advanced Eye Care, 3500 U.S. 1, Vero Beach, FL, 32968, USA.
      [3 ] Stanford University, 300 Pasteur Drive, Stanford, CA, 94305, USA.
      [4 ] Wills Eye Hospital, 840 Walnut Street Suite 1110, Philadelphia, PA, 19107, USA.
      [5 ] Icahn School of Medicine at Mount Sinai, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th Street, New York, NY, 10003, USA. james.tsai@mssm.edu.
      Journal
      Graefes Arch. Clin. Exp. Ophthalmol.
      Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
      Springer Nature
      1435-702X
      0721-832X
      Jun 2017
      : 255
      : 6
      28389703
      10.1007/s00417-017-3649-2
      10.1007/s00417-017-3649-2

      Injection, 5-FU, Ahmed glaucoma implant, Glaucoma

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