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      Is a ‘COVID-19 free’ hospital the answer to resuming elective surgery during the current pandemic? Results from the first available prospective study.

      research-article
      , Dr, MD , Dr, MD , Dr, MBBS BSc FRCS RCPathME , Dr, MD
      Surgery
      Published by Elsevier Inc.
      Elective Surgery, COVID-19, Non-urgent surgery, COVID-19-free hospital, COVID free, Outcomes

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          Abstract

          Background

          Resumption of elective surgery during the current Coronavirus disease 2019 (COVID-19) pandemic crisis has been debated widely and largely discouraged. The aim of this prospective cohort study was to assess the feasibility of resuming elective operations during the current and possible future peaks of this COVID-19 pandemic.

          Methods

          We collected data during the peak of the current pandemic in the United Kingdom on adult patients who underwent elective surgery in a ‘COVID-19 free’ hospital from 8 th April to 29 th May 2020. The study included patients from various surgical specialities. Non-elective and pediatric cases were excluded. The primary outcome was 30-day mortality post operatively. Secondary outcomes were the rate of COVID-19 infections, new onset of pulmonary symptoms after hospitalisation, and requirement for admission to the Intensive Care Unit (ICU).

          Results

          A total of 309 consecutive adult patients were included in this study. No patients died nor required ICU admission. Operations graded ‘Intermediate’ were the most commonly performed procedure representing 91% of the total number. One patient was diagnosed with COVID-19 infection after being transferred to the nearest local emergency hospital for management of post-operative pain secondary to common bile duct stone and was successfully treated conservatively on the ward. No patient developed pulmonary complications. Three patients were admitted for greater than 23 hours. 27 patients (8.7%) developed complications. Complications graded as 2 and 3 according to the Clavien-Dindo’ classification occurred in 14 and 2 patients, respectively.

          Conclusions

          This prospective study shows that, despite the severity and high transmissibility of novel coronavirus 2 (SARS-CoV-2) disease, ‘COVID-19 free’ hospitals can represent a safe setting to resume many types of elective surgery during the peak of a pandemic.

          Highlights

          • This is the first prospective data on resumed elective surgery performed in a ‘COVID-19 free’ hospital. The importance of this study is that, despite the severity and high transmissibility of SARS-CoV-2 disease, ‘COVID-19 free’ hospitals in the independent sector represent a safe setting to resume elective surgery during the peak of a pandemic.

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          Most cited references4

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          Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

          There is limited information describing the presenting characteristics and outcomes of US patients requiring hospitalization for coronavirus disease 2019 (COVID-19).
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            Covid-19: all non-urgent elective surgery is suspended for at least three months in England.

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              Is Open Access

              Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection

              Background The outbreak of 2019 novel coronavirus disease (COVID-19) in Wuhan, China, has spread rapidly worldwide. In the early stage, we encountered a small but meaningful number of patients who were unintentionally scheduled for elective surgeries during the incubation period of COVID-19. We intended to describe their clinical characteristics and outcomes. Methods We retrospectively analyzed the clinical data of 34 patients underwent elective surgeries during the incubation period of COVID-19 at Renmin Hospital, Zhongnan Hospital, Tongji Hospital and Central Hospital in Wuhan, from January 1 to February 5, 2020. Findings Of the 34 operative patients, the median age was 55 years (IQR, 43–63), and 20 (58·8%) patients were women. All patients developed COVID-19 pneumonia shortly after surgery with abnormal findings on chest computed tomographic scans. Common symptoms included fever (31 [91·2%]), fatigue (25 [73·5%]) and dry cough (18 [52·9%]). 15 (44·1%) patients required admission to intensive care unit (ICU) during disease progression, and 7 patients (20·5%) died after admission to ICU. Compared with non-ICU patients, ICU patients were older, were more likely to have underlying comorbidities, underwent more difficult surgeries, as well as more severe laboratory abnormalities (eg, hyperleukocytemia, lymphopenia). The most common complications in non-survivors included ARDS, shock, arrhythmia and acute cardiac injury. Interpretation In this retrospective cohort study of 34 operative patients with confirmed COVID-19, 15 (44·1%) patients needed ICU care, and the mortality rate was 20·5%. Funding National Natural Science Foundation of China.
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                Author and article information

                Contributors
                Role: PGCert Surgery
                Journal
                Surgery
                Surgery
                Surgery
                Published by Elsevier Inc.
                0039-6060
                1532-7361
                15 July 2020
                15 July 2020
                Affiliations
                [1]General and Emergency Surgery Registrar Buckinghamshire Healthcare NHS Trust Stoke Mandeville Hospital Aylesbury HP21 8AL
                [2]LAS Core Surgical Trainee Year 1 Stoke Mandeville Hospital Aylesbury HP21 8AL
                [3]Consultant General Surgery Stoke Mandeville Hospital Aylesbury HP21 8AL
                [4]Consultant Emergency Surgery Stoke Mandeville Hospital Aylesbury HP21 8AL
                Author notes
                []Correspondent CO-authors and request for reprints emanuele.gammeri@ 123456nhs.net
                Article
                S0039-6060(20)30434-7
                10.1016/j.surg.2020.07.003
                7362797
                32739140
                37ac8eed-9a75-4ac0-a398-07abf897fabd
                Crown Copyright © 2020 Published by Elsevier Inc. All rights reserved.

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

                History
                : 1 July 2020
                : 5 July 2020
                Categories
                Article

                elective surgery,covid-19,non-urgent surgery,covid-19-free hospital,covid free,outcomes

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