9
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Epidemiological pattern of orthopaedic fracture during the COVID-19 pandemic: A systematic review and meta-analysis

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Introduction

          This systematic review and meta-analysis aimed evaluate the 30-day mortality, number and site of fracture, mechanism of injury, and location where injury was sustained during the pandemic compared to pre-pandemic.

          Methods

          We performed a systematic literature search from PubMed and Embase on original articles, research letters, and short reports which have data about the number of fractures, site of fracture, mechanism of injury, location where injury was sustained, percentage of operative intervention, mortality during the pandemic compared to a specified period of time before the pandemic. The search was finalized in October 14, 2020.

          Results

          A total of 11,936 participants from 16 studies were included in our study. The pooled analysis indicated a higher 30-days mortality associated with fractures during the pandemic (9% vs 4%, OR 1.86 [1.05, 3.27], p = 0.03; I 2: 36%, p = 0.15). The number of fractures presenting to hospitals has declined 43% (35–50%) compared to pre-pandemic. Hand fracture was fewer during the pandemic (18% vs 23%, OR 0.75 [0.58, 0.97], p = 0.03; I 2: 69%, p = 0.002). Work-related traumas, high-energy falls, and domestic accidents were more common during the pandemic, while sports-related traumas were found to be less. Injuries that occurred in the sports area were lower than before the pandemic.

          Conclusion

          The present meta-analysis showed that during the COVID-19 pandemic, the number of fractures has decreased, but there is a higher mortality rate associated with fractures.

          Related collections

          Most cited references41

          • Record: found
          • Abstract: found
          • Article: not found

          Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia – A systematic review, meta-analysis, and meta-regression ☆

          Background and aims Diabetes Mellitus (DM) is chronic conditions with devastating multi-systemic complication and may be associated with severe form of Coronavirus Disease 2019 (COVID-19). We conducted a systematic review and meta-analysis in order to investigate the association between DM and poor outcome in patients with COVID-19 pneumonia. Methods Systematic literature search was performed from several electronic databases on subjects that assess DM and outcome in COVID-19 pneumonia. The outcome of interest was composite poor outcome, including mortality, severe COVID-19, acute respiratory distress syndrome (ARDS), need for intensive care unit (ICU) care, and disease progression. Results There were a total of 6452 patients from 30 studies. Meta-analysis showed that DM was associated with composite poor outcome (RR 2.38 [1.88, 3.03], p < 0.001; I2: 62%) and its subgroup which comprised of mortality (RR 2.12 [1.44, 3.11], p < 0.001; I2: 72%), severe COVID-19 (RR 2.45 [1.79, 3.35], p < 0.001; I2: 45%), ARDS (RR 4.64 [1.86, 11.58], p = 0.001; I2: 9%), and disease progression (RR 3.31 [1.08, 10.14], p = 0.04; I2: 0%). Meta-regression showed that the association with composite poor outcome was influenced by age (p = 0.003) and hypertension (p < 0.001). Subgroup analysis showed that the association was weaker in studies with median age ≥55 years-old (RR 1.92) compared to <55 years-old (RR 3.48), and in prevalence of hypertension ≥25% (RR 1.93) compared to <25% (RR 3.06). Subgroup analysis on median age <55 years-old and prevalence of hypertension <25% showed strong association (RR 3.33) Conclusion DM was associated with mortality, severe COVID-19, ARDS, and disease progression in patients with COVID-19.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Impact of the COVID-19 Pandemic on an Emergency Traumatology Service: Experience at a Tertiary Trauma Centre in Spain

            Highlights • Contingency plans need to be careful when reallocating resources, and not assume that all trauma presentations will decrease during a State of Emergency. • Health problems such as osteoporotic hip fractures may in fact remain stable during the State of Emergency (implementation of stringent lock-down measures for the population). • Given that osteoporotic hip fractures are in elderly population with multiple comorbidities, operative delays may increase the risk of mortality as well as of nosocomial infections in this pandemic virus.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Impact of Cerebrovascular and Cardiovascular Diseases on Mortality and Severity of COVID-19 – Systematic Review, Meta-analysis, and Meta-regression

              Highlights • Cerebrovascular was associated with increased mortality and borderline increase in severity of COVID-19. • Cardiovascular was associated with increased mortality and severity of COVID-19. • Gender, age, hypertension, diabetes, and respiratory comorbidities did not influence the association • The association between cerebrovascular disease and poor outcome in COVID-19 was not affected by cardiovascular diseases and vice versa.
                Bookmark

                Author and article information

                Journal
                J Clin Orthop Trauma
                J Clin Orthop Trauma
                Journal of Clinical Orthopaedics and Trauma
                Delhi Orthopedic Association.
                0976-5662
                2213-3445
                30 December 2020
                30 December 2020
                Affiliations
                [a ]Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia
                [b ]Department of Orthopaedic and Traumatology, Faculty of Medicine, Universitas Udayana, Bali, Indonesia
                Author notes
                []Corresponding author.
                Article
                S0976-5662(20)30591-9
                10.1016/j.jcot.2020.12.028
                7773000
                33398227
                37ee34c8-63ce-47f1-8bd4-3f258eca1334
                © 2020 Delhi Orthopedic Association. All rights reserved.

                Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

                History
                : 12 December 2020
                : 27 December 2020
                Categories
                Article

                covid-19,fracture,trauma,orthopaedic,epidemiology
                covid-19, fracture, trauma, orthopaedic, epidemiology

                Comments

                Comment on this article