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      Natural killer cells, viruses and cancer.

      1 ,
      Nature reviews. Immunology
      Springer Science and Business Media LLC

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          Abstract

          Natural killer cells are innate immune cells that control certain microbial infections and tumours. The function of natural killer cells is regulated by a balance between signals transmitted by activating receptors, which recognize ligands on tumours and virus-infected cells, and inhibitory receptors specific for major histocompatibility complex class I molecules. Here, we review the emerging evidence that natural killer cells have an important role in vivo in immune defence.

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          Author and article information

          Journal
          Nat Rev Immunol
          Nature reviews. Immunology
          Springer Science and Business Media LLC
          1474-1733
          1474-1733
          Oct 2001
          : 1
          : 1
          Affiliations
          [1 ] Department of Microbiology and Immunology and the Cancer Research Institute, University of California, San Francisco, 94143-0414, USA.
          Article
          10.1038/35095564
          11905813
          37ee6931-ce60-42e2-9164-004c5608c243
          History

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