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      Co-occurring self-efficacy, anxiety, and depression in caregivers of patients with heart failure: A Group-Based Dual-Trajectory Modeling Approach

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          Abstract

          Background

          Self-efficacy and mental health present mutually influencing relationships in caregivers of patients with heart failure (HF). There is currently a lack of understanding the synergistic developmental mechanisms of self-efficacy, anxiety, and depression in caregivers. The purpose of the study was to examine the individual and dual trajectories of caregiver self-efficacy, anxiety, and depression during the first three months after the discharge of patients with HF.

          Methods

          A prospective cohort study was conducted from June 2022 to May 2024, in four tertiary hospitals in Tianjin, China. A total of 299 family caregivers of patients with HF were enrolled in the cohort, and 267 completed follow-ups. Group-based dual trajectory modeling was employed to examine the development of self-efficacy, anxiety, and depression.

          Results

          The mean (SD) age of caregivers was 58.3 (13.1) years, and 164 (61.4%) were women. Three trajectories of caregiver self-efficacy were identified: low-curve (25.1%), middle-curve (67.8%), and high-stable (7.1%). Regular exercise, work status, and chronic disease were associated with the different caregiver self-efficacy trajectories. A 3-class trajectory solution was chosen for depression and anxiety when analyzed separately. The proportions of ideal combinations of high-stable self-efficacy and initial-to-mild anxiety or depression were extremely small, at 12.60% and 8.00%, respectively. Caregivers had limited and inconsistent abilities to regulate the effects of anxiety and depression on their self-efficacy.

          Conclusion

          The present study identified three distinct trajectories of self-efficacy, anxiety, and depression among family caregivers of patients with HF. The dual-trajectory models revealed the probability of interrelationships between caregiver self-efficacy trajectories and those of anxiety and depression, suggesting substantial opportunities to enhance caregivers’ self-efficacy and mental well-being of patients with HF.

          Supplementary information

          The online version contains supplementary material available at 10.1186/s12912-025-02995-0.

          Related collections

          Most cited references41

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          G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences

          G*Power (Erdfelder, Faul, & Buchner, 1996) was designed as a general stand-alone power analysis program for statistical tests commonly used in social and behavioral research. G*Power 3 is a major extension of, and improvement over, the previous versions. It runs on widely used computer platforms (i.e., Windows XP, Windows Vista, and Mac OS X 10.4) and covers many different statistical tests of the t, F, and chi2 test families. In addition, it includes power analyses for z tests and some exact tests. G*Power 3 provides improved effect size calculators and graphic options, supports both distribution-based and design-based input modes, and offers all types of power analyses in which users might be interested. Like its predecessors, G*Power 3 is free.
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            A brief measure for assessing generalized anxiety disorder: the GAD-7.

            Generalized anxiety disorder (GAD) is one of the most common mental disorders; however, there is no brief clinical measure for assessing GAD. The objective of this study was to develop a brief self-report scale to identify probable cases of GAD and evaluate its reliability and validity. A criterion-standard study was performed in 15 primary care clinics in the United States from November 2004 through June 2005. Of a total of 2740 adult patients completing a study questionnaire, 965 patients had a telephone interview with a mental health professional within 1 week. For criterion and construct validity, GAD self-report scale diagnoses were compared with independent diagnoses made by mental health professionals; functional status measures; disability days; and health care use. A 7-item anxiety scale (GAD-7) had good reliability, as well as criterion, construct, factorial, and procedural validity. A cut point was identified that optimized sensitivity (89%) and specificity (82%). Increasing scores on the scale were strongly associated with multiple domains of functional impairment (all 6 Medical Outcomes Study Short-Form General Health Survey scales and disability days). Although GAD and depression symptoms frequently co-occurred, factor analysis confirmed them as distinct dimensions. Moreover, GAD and depression symptoms had differing but independent effects on functional impairment and disability. There was good agreement between self-report and interviewer-administered versions of the scale. The GAD-7 is a valid and efficient tool for screening for GAD and assessing its severity in clinical practice and research.
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              The PHQ-9: validity of a brief depression severity measure.

              While considerable attention has focused on improving the detection of depression, assessment of severity is also important in guiding treatment decisions. Therefore, we examined the validity of a brief, new measure of depression severity. The Patient Health Questionnaire (PHQ) is a self-administered version of the PRIME-MD diagnostic instrument for common mental disorders. The PHQ-9 is the depression module, which scores each of the 9 DSM-IV criteria as "0" (not at all) to "3" (nearly every day). The PHQ-9 was completed by 6,000 patients in 8 primary care clinics and 7 obstetrics-gynecology clinics. Construct validity was assessed using the 20-item Short-Form General Health Survey, self-reported sick days and clinic visits, and symptom-related difficulty. Criterion validity was assessed against an independent structured mental health professional (MHP) interview in a sample of 580 patients. As PHQ-9 depression severity increased, there was a substantial decrease in functional status on all 6 SF-20 subscales. Also, symptom-related difficulty, sick days, and health care utilization increased. Using the MHP reinterview as the criterion standard, a PHQ-9 score > or =10 had a sensitivity of 88% and a specificity of 88% for major depression. PHQ-9 scores of 5, 10, 15, and 20 represented mild, moderate, moderately severe, and severe depression, respectively. Results were similar in the primary care and obstetrics-gynecology samples. In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 is also a reliable and valid measure of depression severity. These characteristics plus its brevity make the PHQ-9 a useful clinical and research tool.

                Author and article information

                Contributors
                xiaoyingzang@163.com
                zhangxiaonan19@163.com
                Journal
                BMC Nurs
                BMC Nurs
                BMC Nursing
                BioMed Central (London )
                1472-6955
                31 March 2025
                31 March 2025
                2025
                : 24
                : 351
                Affiliations
                [1 ]School of Nursing, Tianjin Medical University, ( https://ror.org/02mh8wx89) No. 22 Qixiangtai Road, Heping District, Tianjin, 300070 China
                [2 ]Department of Nursing, The Second Hospital of Tianjin Medical University, ( https://ror.org/03rc99w60) Tianjin, China
                [3 ]Department of Nursing, Tianjin Medical University General Hospital, ( https://ror.org/003sav965) Tianjin, China
                [4 ]Department of Cardiology, The Second Hospital of Tianjin Medical University, ( https://ror.org/03rc99w60) Tianjin, China
                Article
                2995
                10.1186/s12912-025-02995-0
                11959719
                40165181
                380b34ad-1467-4ae6-9f9d-5e740f5b672a
                © The Author(s) 2025

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 22 July 2024
                : 17 March 2025
                Categories
                Research
                Custom metadata
                © BioMed Central Ltd., part of Springer Nature 2025

                Nursing
                heart failure,caregivers,self-efficacy,depression,anxiety
                Nursing
                heart failure, caregivers, self-efficacy, depression, anxiety

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