Changes in Systolic Time Intervals during Physical Training in Patients with Ischemic Heart Disease

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Abstract

Systolic time intervals (STI) were measured at rest before and after an exercise training programme in 37 patients with ischemic heart disease; 17 patients were treated with a β-blocking drug (BB-group) and 20 were not (nBB-group). After the training period peak oxygen uptake had increased by 37% in the BB-patients and by 41 % in the nBB-group. During the training period electromechanical systole (QS<sub>2</sub>) and pre-ejection period (PEP), when corrected for heart rate, shortened significantly in all 37 patients. Left ventricular ejection time (LVET) increased but when corrected for heart rate no significant changes occurred. The ratio of PEP/LVET decreased significantly. The changes in STI were similar in the patients treated with β-blocking drugs than in those without such treatment. The changes in STI in both groups suggest that left ventricular function improves during the training period and that β-adrenergic blockade does not alter this outcome.

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Author and article information

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1984

Publication date (Print): 1984

Publication date (Electronic): 11 November 2008

Volume: 71

Issue: 4

Pages: 207-214

Affiliations

^aHypertension and Cardiovascular Rehabilitation Unit and ^bDivision of Cardiology, Department of Pathophysiology, Internal Medicine, Cardiology, University of Leuven, Belgium

Article

Publisher ID: 173666 Other ID: Cardiology 1984;71:207–214

DOI: 10.1159/000173666

PubMed ID: 6148142

SO-VID: 382c7d49-f9c2-42c5-b251-a4750bf6395b

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 15 September 1983

Date accepted : 19 February 1984

Page count

Pages: 8

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