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      Changes in Systolic Time Intervals during Physical Training in Patients with Ischemic Heart Disease

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          Abstract

          Systolic time intervals (STI) were measured at rest before and after an exercise training programme in 37 patients with ischemic heart disease; 17 patients were treated with a β-blocking drug (BB-group) and 20 were not (nBB-group). After the training period peak oxygen uptake had increased by 37% in the BB-patients and by 41 % in the nBB-group. During the training period electromechanical systole (QS<sub>2</sub>) and pre-ejection period (PEP), when corrected for heart rate, shortened significantly in all 37 patients. Left ventricular ejection time (LVET) increased but when corrected for heart rate no significant changes occurred. The ratio of PEP/LVET decreased significantly. The changes in STI were similar in the patients treated with β-blocking drugs than in those without such treatment. The changes in STI in both groups suggest that left ventricular function improves during the training period and that β-adrenergic blockade does not alter this outcome.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1984
          1984
          11 November 2008
          : 71
          : 4
          : 207-214
          Affiliations
          aHypertension and Cardiovascular Rehabilitation Unit and bDivision of Cardiology, Department of Pathophysiology, Internal Medicine, Cardiology, University of Leuven, Belgium
          Article
          173666 Cardiology 1984;71:207–214
          10.1159/000173666
          6148142
          © 1984 S. Karger AG, Basel

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          Page count
          Pages: 8
          Categories
          Exercise Testing and Rehabilitation

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