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      Treatment-Related Adverse Events of PD-1 and PD-L1 Inhibitors in Clinical Trials : A Systematic Review and Meta-analysis

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          Abstract

          Programmed cell death (PD-1) and programmed cell death ligand 1 (PD-L1) inhibitors have been increasingly used in cancer therapy. Understanding the treatment-related adverse events of these drugs is critical for clinical practice.

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          Author and article information

          Journal
          JAMA Oncology
          JAMA Oncol
          American Medical Association (AMA)
          2374-2437
          April 25 2019
          Affiliations
          [1 ]Division of Hematology, Mayo Clinic, Rochester, Minnesota
          [2 ]Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota
          [3 ]Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston
          [4 ]Department of Public Health Sciences, Pennsylvania State College of Medicine, Hershey
          [5 ]Medical School of Nanjing University, Nanjing, China
          [6 ]The Comprehensive Cancer Centre of Drum Tower Hospital, Clinical Cancer Institute of Nanjing University, Nanjing, China
          [7 ]Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston
          [8 ]Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
          [9 ]West Cancer Center, The University of Tennessee, Memphis
          [10 ]Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston
          Article
          10.1001/jamaoncol.2019.0393
          6487913
          31021376
          3892eafd-ffac-4838-8a3c-406fea305e50
          © 2019
          History

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