Dual role of leukotriene B4 receptor type 1 in experimental sepsis.

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

The controversial results from different studies suggested that leukocyte recruitment mediated by leukotriene B4 (LTB4) and its receptor might improve pathogen clearance, but might also aggravate organ injury during sepsis. The present study was performed to compare the effect of BLT1 ligand LTB4 and its antagonist U-75302 on the development of sepsis.

Related collections

Author and article information

Journal

Journal ID (iso-abbrev): J. Surg. Res.

Title: The Journal of surgical research

ISSN (Electronic): 1095-8673

ISSN (Print): 0022-4804

Publication date (Electronic): Feb 2015

Volume: 193

Issue: 2

Affiliations

[1 ] Department of Anesthesiology and Intensive Care, Changhai Hospital, Second Military Medical University, Shanghai, China.

[2 ] Department of Gastroenterology, Changhai Hospital, Second Military Medical University, Shanghai, China.

[3 ] Department of Anesthesiology and Intensive Care, Shanghai Ninth People's Hospital, Shanghai Jiaotong University, Shanghai, China.

[4 ] Department of Anesthesiology and Intensive Care, Changhai Hospital, Second Military Medical University, Shanghai, China. Electronic address: jfwang@smmu.edu.cn.

[5 ] Department of Anesthesiology and Intensive Care, Changhai Hospital, Second Military Medical University, Shanghai, China. Electronic address: deng_x@yahoo.com.

Article

Publisher Item ID: S0022-4804(14)00868-3

DOI: 10.1016/j.jss.2014.09.013

PubMed ID: 25439504

SO-VID: 38c106b1-f86e-4888-8b2c-ca3ce1d3bcd2

History

Keywords: BLT1,Leukotriene B4,Sepsis,Survival

Data availability:

Keywords: BLT1, Leukotriene B4, Sepsis, Survival

Comments

Comment on this article

scite_

Cited by 9

See all cited by

- Version 1