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      Influence of Postural Changes on the Glomerular Filtration Rate in Nephroptosis

      , ,

      Nephron

      S. Karger AG

      Postural changes, Glomerular filtration rate, Nephroptosis, Orthostatic hypertension

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          Abstract

          The influence of postural changes on renal function was determined in 13 patients with nephroptosis and in 5 normal subjects by measuring GFR in the erect and supine positions. The result indicate that GFR was reduced in the erect position in 10 of 13 patients with either unilateral or bilateral nephroptosis whereas GFR was increased in the erect position in 4 of 5 patients without renal disease. One patient with bilateral nephroptosis and renovascular hypertension was studied before and after surgical correction of his desease. These observations indicate that patients with nephroptosis may have significant reductions in renal function when they assume an upright position, and suggest that GFR measurements in the supine and erect position in patients with nephroptosis can be helpful in evaluating this disease.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1976
          1976
          28 November 2008
          : 16
          : 3
          : 161-172
          Affiliations
          2nd Medical Clinic, CNR Clinical Physiology Laboratory, University of Pisa, Pisa
          Article
          180598 Nephron 1976;16:161–172
          10.1159/000180598
          1244574
          © 1976 S. Karger AG, Basel

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          Page count
          Pages: 12
          Categories
          Paper

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