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      Mechanically active materials in three-dimensional mesostructures

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          Abstract

          We integrate multiple, independently addressable piezoelectric thin-film actuators into complex, 3D mesostructures.

          Abstract

          Complex, three-dimensional (3D) mesostructures that incorporate advanced, mechanically active materials are of broad, growing interest for their potential use in many emerging systems. The technology implications range from precision-sensing microelectromechanical systems, to tissue scaffolds that exploit the principles of mechanobiology, to mechanical energy harvesters that support broad bandwidth operation. The work presented here introduces strategies in guided assembly and heterogeneous materials integration as routes to complex, 3D microscale mechanical frameworks that incorporate multiple, independently addressable piezoelectric thin-film actuators for vibratory excitation and precise control. The approach combines transfer printing as a scheme for materials integration with structural buckling as a means for 2D-to-3D geometric transformation, for designs that range from simple, symmetric layouts to complex, hierarchical configurations, on planar or curvilinear surfaces. Systematic experimental and computational studies reveal the underlying characteristics and capabilities, including selective excitation of targeted vibrational modes for simultaneous measurements of viscosity and density of surrounding fluids. The results serve as the foundations for unusual classes of mechanically active 3D mesostructures with unique functions relevant to biosensing, mechanobiology, energy harvesting, and others.

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          Most cited references45

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          Frequency response of cantilever beams immersed in viscous fluids with applications to the atomic force microscope

          John Sader (1998)
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            Printing, folding and assembly methods for forming 3D mesostructures in advanced materials

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              Single-protein nanomechanical mass spectrometry in real time

              Nanoelectromechanical systems (NEMS) resonators can detect mass with exceptional sensitivity. Previously, mass spectra from several hundred adsorption events were assembled in NEMS-based mass spectrometry using statistical analysis. Here, we report the first realization of single-molecule NEMS-based mass spectrometry in real time. As each molecule in the sample adsorbs upon the NEMS resonator, its mass and the position-of-adsorption are determined by continuously tracking two driven vibrational modes of the device. We demonstrate the potential of multimode NEMS-based mass spectrometry by analyzing IgM antibody complexes in real-time. NEMS-MS is a unique and promising new form of mass spectrometry: it can resolve neutral species, provides resolving power that increases markedly for very large masses, and allows acquisition of spectra, molecule-by-molecule, in real-time.
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                Author and article information

                Journal
                Sci Adv
                Sci Adv
                SciAdv
                advances
                Science Advances
                American Association for the Advancement of Science
                2375-2548
                September 2018
                14 September 2018
                : 4
                : 9
                : eaat8313
                Affiliations
                [1 ]Department of Materials Science and Engineering, Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
                [2 ]Simpson Querrey Institute and Feinberg Medical School, Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.
                [3 ]Departments of Civil and Environmental Engineering and Mechanical Engineering, Northwestern University, Evanston, IL 60208, USA.
                [4 ]Advanced Composites Centre for Innovation and Science, University of Bristol, Bristol BS8 1TR, UK.
                [5 ]Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
                [6 ]Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
                [7 ]State Key Laboratory for Strength and Vibration of Mechanical Structures, Xi’an Jiaotong University, Xi’an, Shaanxi 710049, China.
                [8 ]Center for Mechanics and Materials, Center for Flexible Electronics Technology, and Applied Mechanics Laboratory, Department of Engineering Mechanics, Tsinghua University, Beijing 100084, China.
                [9 ]Department of Materials Science and Engineering, Biomedical Engineering, Neurological Surgery, Chemistry, Mechanical Engineering, Electrical Engineering and Computer Science, Northwestern University, Evanston, IL 60208, USA.
                Author notes
                [*]

                These authors contributed equally to this work.

                []Corresponding author. Email: jrogers@ 123456northwestern.edu (J.A.R.); yihuizhang@ 123456tsinghua.edu.cn (Y.Z.)
                Author information
                http://orcid.org/0000-0002-9432-3665
                http://orcid.org/0000-0003-0522-1171
                http://orcid.org/0000-0001-7859-5153
                http://orcid.org/0000-0001-6136-7277
                http://orcid.org/0000-0001-6818-7674
                http://orcid.org/0000-0002-1968-5092
                http://orcid.org/0000-0001-6058-3007
                http://orcid.org/0000-0002-0628-5735
                http://orcid.org/0000-0003-0722-1108
                http://orcid.org/0000-0002-6104-7692
                http://orcid.org/0000-0002-5934-9026
                http://orcid.org/0000-0001-9242-8474
                http://orcid.org/0000-0003-2720-9712
                http://orcid.org/0000-0002-0483-8359
                http://orcid.org/0000-0003-0885-2067
                http://orcid.org/0000-0002-3830-5980
                Article
                aat8313
                10.1126/sciadv.aat8313
                6140627
                30225368
                39073a67-6170-4b16-bf03-7c0cc0360326
                Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

                This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

                History
                : 22 April 2018
                : 01 August 2018
                Funding
                Funded by: doi http://dx.doi.org/10.13039/100000001, National Science Foundation;
                Award ID: CMMI1400169, CMMI1534120 and CMMI1635443
                Funded by: doi http://dx.doi.org/10.13039/100000002, National Institutes of Health;
                Award ID: R01EB019337
                Funded by: doi http://dx.doi.org/10.13039/100000015, U.S. Department of Energy;
                Award ID: DE-FG02-07ER46471
                Funded by: doi http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
                Award ID: 11722217
                Funded by: doi http://dx.doi.org/10.13039/501100001809, National Natural Science Foundation of China;
                Award ID: 11320101001
                Funded by: National Basic Research Program of China;
                Award ID: 2015CB351900
                Categories
                Research Article
                Research Articles
                SciAdv r-articles
                Materials Science
                Applied Sciences and Engineering
                Materials Science
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