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      Inhibitory Effect of Rhodomyrtus tomentosa Methanolic Leaves Extract on P-selectin Platelet Aggregation of ABO Blood Group by ELISA Method

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      Environment-Behaviour Proceedings Journal
      e-IPH Ltd.

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          Abstract

          In light of discovering the new antiplatelet from the natural source, this study was undertaken to determine the inhibitory effect of Rhodomyrtus tomentosa methanolic leaves extracts on P-selectin platelet aggregation of the ABO blood group. Whole blood samples from each blood group were collected tested with different concentration of leaves extract by using ELISA method. The inhibition was considered to occur if the values of concentration P selectin detected below 1.56 ng/ml. Instead of inhibiting the P-selectin expression as antiplatelet, Rhodomyrtus tomentosaaccelerates the P-selectin expression as an agonist in a dose-dependent manner. In conclusion, no antiplatelet effects were seen.

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          Author and article information

          Journal
          Environment-Behaviour Proceedings Journal
          E-BPJ
          e-IPH Ltd.
          2398-4287
          March 01 2019
          March 01 2019
          : 4
          : 10
          : 79
          Article
          10.21834/e-bpj.v4i10.1626
          390c8b18-28f2-4d75-a593-200cd23cc59b
          © 2019

          This work is licensed under a Creative Commons Attribution 4.0 Unported License. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/


          Psychology,Urban design & Planning,Urban studies,General behavioral science,Cultural studies

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