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      Review: comparison of PET rubidium-82 with conventional SPECT myocardial perfusion imaging

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          Abstract

          Nuclear cardiology has for many years been focused on gamma camera technology. With ever improving cameras and software applications, this modality has developed into an important assessment tool for ischaemic heart disease. However, the development of new perfusion tracers has been scarce. While cardiac positron emission tomography (PET) so far largely has been limited to centres with on-site cyclotron, recent developments with generator produced perfusion tracers such as rubidium-82, as well as an increasing number of PET scanners installed, may enable a larger patient flow that may supersede that of gamma camera myocardial perfusion imaging.

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          Most cited references61

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          Guidelines on myocardial revascularization.

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            ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging).

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              Does rubidium-82 PET have superior accuracy to SPECT perfusion imaging for the diagnosis of obstructive coronary disease?: A systematic review and meta-analysis.

              The purpose of this study was to evaluate the accuracy of rubidium (Rb)-82 positron emission tomography (PET) for the diagnosis of obstructive coronary artery disease (CAD) in comparison to single-photon emission tomography (SPECT).
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                Author and article information

                Journal
                Clin Physiol Funct Imaging
                Clin Physiol Funct Imaging
                cpf
                Clinical Physiology and Functional Imaging
                BlackWell Publishing Ltd (Oxford, UK )
                1475-0961
                1475-097X
                May 2014
                13 September 2013
                : 34
                : 3
                : 163-170
                Affiliations
                Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen Copenhagen, Denmark
                Author notes
                Correspondence Adam A. Ghotbi, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark, E-mail: adamghotbi@ 123456gmail.com
                Article
                10.1111/cpf.12083
                4204510
                24028171
                39304a85-e8cf-409c-baa2-990a2835b889
                © 2013 The Authors. Clinical Physiology and Functional Imaging published by John Wiley & Sons Ltd on behalf of the Scandinavian Society of Clinical Physiology and Nuclear Medicine.

                This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

                History
                : 11 April 2013
                : 14 August 2013
                Categories
                Invited Reviews

                Anatomy & Physiology
                cardiac pet,cardiac spect,cardiology,myocardial perfusion imaging,rubidium
                Anatomy & Physiology
                cardiac pet, cardiac spect, cardiology, myocardial perfusion imaging, rubidium

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