Die experimentelle Ornithosepneumonie der Maus und ihre Pathomorphose unter der Antibiose

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Abstract

The intratracheal injection of an ornithosal strain (isolated from human sputum) given to white mice resulted in pneumonia in 70 %. They showed a characteristic pattern of an alveolar and granulomatous pneumonia Therapy with terramycin which started 2 h after infection led to a decrease of pneumonia, in severe as well as in fatal forms. Treatment with terramycin 24 h after infection resulted only in a decrease of severe forms. Chemotherapy changed the morphologic pattern of pneumonias with only an uncharacteristicinterstitial inflammation observed.

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Author and article information

Journal

Journal ID (publisher-id): PAT

Journal ID (nlm-ta): Pathobiology

Journal ID (doi): 10.1159/issn.1015-2008

Title: Pathobiology

Publisher: S. Karger AG

ISSN (Print): 1015-2008

ISSN (Electronic): 1423-0291

Publication date Subscription-year: 1974

Publication date (Print): 1974

Publication date (Electronic): 03 October 2008

Volume: 40

Issue: 1

Pages: 43-53

Affiliations

Pathologisch-Bakteriologisches Institut des Bezirkskrankenhauses St. Georg, Leipzig, und Fachgruppe Veterinär-Mikrobiologie und Tierseuchenlehre der Karl-Marx- Universität, Leipzig

Article

Publisher ID: 162499 Other ID: Pathol Microbiol (Basel) 1974;40:43–53

DOI: 10.1159/000162499

SO-VID: 395095fa-f8db-4ee5-9369-4582bee40389

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 19 December 1972

Date accepted : 31 January 1973

Page count

Pages: 11

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