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      Myxoedema Crisis

      Hormone Research in Paediatrics

      S. Karger AG

      Hypothermia, Coma, Stress factors

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          Abstract

          Fourteen cases of myxoedema crisis have been reportedand 93 additional cases have been collected from the literature. Hypothermia, coma and shock have been identified as the main clinical features of crisis. It has been pointed out that while clouding of consciousness is universal, coma is of doubtful prognostic significance. The importance of hypothermia in prognosis has been stressed. Various stress factors have been described which may initiate crisis especially respiratory infections and epileptic fits. The urgency of adequate treatment has been emphasised but overenthusiastic treatment is only slightly less dangerous than delay and inadequate treatment. However, even the best available treatment will only lead to a moderate improvement in outlook and the only successful way is prevention.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          1663-2818
          1663-2826
          1970
          1970
          21 November 2008
          : 1
          : 2
          : 110-128
          Affiliations
          Reading Combined Hospitals and Endocrine Clinic, Royal Berkshire Hospital
          Article
          178177 Hormones 1970;1:110–128
          10.1159/000178177
          © 1970 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 19
          Categories
          Paper

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