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      Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer

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      Fertility and Sterility
      Elsevier BV

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          Abstract

          To determine the relationship between blastocyst score and pregnancy outcome. Retrospective review of blastocyst transfer in an IVF clinic. Private assisted reproductive technology unit. 107 patients undergoing blastocyst culture and transfer of two embryos. Culture of all pronucleate embryos in sequential media to the blastocyst stage (day 5), followed by transfer of two blastocysts. Implantation rates, pregnancy rates, and twinning were analyzed. When a patient received two top-scoring blastocysts (64% of patients), implantation and pregnancy rates were 70% and 87%, respectively. The twinning rate in this group was 61%. When only one top-quality blastocyst was available for transfer (21% of patients), the implantation and pregnancy rates were 50% and 70%. The twinning rate for this group was 50%. In contrast, when only low-scoring blastocysts were available for transfer (15% of patients), implantation and pregnancy rates were 28% and 44%, and the twinning rate was 29%. No monozygotic twins were observed in this group of patients. The ability to transfer one high-scoring blastocyst should lead to pregnancy rates greater than 60%, without the complication of twins.

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          Author and article information

          Journal
          Fertility and Sterility
          Fertility and Sterility
          Elsevier BV
          00150282
          June 2000
          June 2000
          : 73
          : 6
          : 1155-1158
          Article
          10.1016/S0015-0282(00)00518-5
          10856474
          39e68522-a98f-4842-b3e8-1c979b671dc4
          © 2000

          https://www.elsevier.com/tdm/userlicense/1.0/

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