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      Antimalarial chemotherapeutic peroxides: artemisinin, yingzhaosu A and related compounds

      , , ,
      International Journal for Parasitology
      Elsevier BV

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          Abstract

          Mechanism-based rational design and gram-scale chemical synthesis have produced some new trioxane and endoperoxide antimalarial drug candidates that are efficacious and safe. This review summarises recent achievements in this area of peroxide drug development for malaria chemotherapy.

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          Author and article information

          Journal
          International Journal for Parasitology
          International Journal for Parasitology
          Elsevier BV
          00207519
          December 2002
          December 2002
          : 32
          : 13
          : 1661-1667
          Article
          10.1016/S0020-7519(02)00195-9
          12435451
          3a4cebcb-29d6-423f-bed5-dcf8d422b509
          © 2002

          https://www.elsevier.com/tdm/userlicense/1.0/

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