QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy.

van Stipdonk, Antonius M. W.; Ter Horst, Iris A H; Kloosterman, Mariëlle; Engels, Elien B.; Rienstra, Michiel; Crijns, Harry J. G. M.; Vos, Marc A.; van Gelder, Isabelle C; Prinzen, Frits W.; Meine, Mathias; Maass, Alexander H.; Vernooy, Kevin

doi:10.1161/CIRCEP.118.006497

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QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy.

Author(s): Antonius M W van Stipdonk ¹ , Iris Ter Horst ¹ ^, ² , Marielle Kloosterman ³ , Elien B Engels ⁴ , Michiel Rienstra ³ , Harry J G M Crijns ¹ ^, ⁴ , Marc A Vos ⁵ , Isabelle C van Gelder ³ , Frits W Prinzen ⁴ , Mathias Meine ² , Alexander H Maass ³ , Kevin Vernooy ¹ ^, ⁴ ^, ⁶

Publication date (Electronic): December 2018

Journal: Circulation. Arrhythmia and electrophysiology

Publisher: Ovid Technologies (Wolters Kluwer Health)

Keywords: bundle-branch block, cardiac resynchronization therapy, heart failure, patient selection, stroke volume

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Abstract

The combination of left bundle branch block (LBBB) morphology and QRS duration is currently used to select patients for cardiac resynchronization therapy (CRT). These parameters, however, have limitations. This study evaluates the value of QRS area compared with that of QRS duration and morphology in the association with clinical and echocardiographic outcomes in a large cohort of CRT patients.

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Journal ID (iso-abbrev): Circ Arrhythm Electrophysiol

Title: Circulation. Arrhythmia and electrophysiology

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1941-3084

ISSN (Print): 1941-3084

Publication date (Electronic): December 2018

Volume: 11

Issue: 12

Affiliations

[1 ] Department of Cardiology, Maastricht University Medical Centre, The Netherlands (A.M.W.v.S., H.J.G.M.C., K.V.).

[2 ] Department of Cardiology, University Medical Centre Utrecht, The Netherlands (I.t.H., M.M.).

[3 ] Department of Cardiology, University Medical Centre Groningen, University of Groningen, The Netherlands (M.K., M.R., I.C.v.G., A.H.M.).

[4 ] Department of Physiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, The Netherlands (E.B.E., H.J.G.M.C., F.W.P., K.V.).

[5 ] Department of Medical Physiology, University of Utrecht, The Netherlands (M.A.V.).

[6 ] Department of Cardiology, Radboud University Medical Centre, Nijmegen, The Netherlands (K.V.).

Article

DOI: 10.1161/CIRCEP.118.006497

PubMed ID: 30541356

SO-VID: 3abc6515-6335-4b21-914b-5ddf488d992b

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Keywords: bundle-branch block,cardiac resynchronization therapy,heart failure,patient selection,stroke volume

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Keywords: bundle-branch block, cardiac resynchronization therapy, heart failure, patient selection, stroke volume

QRS Area Is a Strong Determinant of Outcome in Cardiac Resynchronization Therapy.

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