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      Late-Onset Adrenal Hyperplasia in North Indian Hirsute Women

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          Abstract

          The occurrence of late-onset congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency was studied in 60 consecutive hirsute women by means of adrenocorticotrophin (ACTH)-stimulated serum 17-hydroxyprogesterone (17-OHP) levels. Five (8.3%) women had an exaggerated response (ACTH-stimulated 17-OHP 3,160 ± 560 ng/dl). All of them had regular periods and 3 were virilised. The other 2 were indistinguishable from those with idiopathic hirsutism or polycystic ovarian disease.

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          Author and article information

          Journal
          Journal ID (publisher-id): HRE
          Journal ID (nlm-ta): Horm Res Paediatr
          Journal ID (doi): 10.1159/issn.1663-2818
          Title: Hormone Research in Paediatrics
          Publisher: S. Karger AG
          ISSN (Print): 1663-2818
          ISSN (Electronic): 1663-2826
          Publication date Subscription-year: 1988
          Publication date (Print): 1988
          Publication date (Electronic): 02 December 2008
          Volume: 30
          Issue: 1
          Pages: 1-4
          Affiliations
          Department of Endocrinology and Metabolism, All-India Institute of Medical Sciences, New Delhi, India
          Article
          Publisher ID: 181016 Other ID: Horm Res 1988;30:1–4
          DOI: 10.1159/000181016
          PubMed ID: 2851524
          SO-VID: 3ae45968-ce1f-4271-86be-101f4e2869bf
          Copyright © © 1988 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Date received : 20 October 1987
          Date accepted : 12 February 1988
          Page count
          Pages: 4
          Categories
          Subject: Original Paper

          ScienceOpen disciplines: Endocrinology & Diabetes,Neurology,Nutrition & Dietetics,Sexual medicine,Internal medicine,Pharmacology & Pharmaceutical medicine
          Keywords: Hirsutism,Late-onset congenital adrenal hyperplasia,ACTH test,21-Hydroxylase deficiency,17-Hydroxyprogesterone
          Data availability:
          ScienceOpen disciplines: Endocrinology & Diabetes, Neurology, Nutrition & Dietetics, Sexual medicine, Internal medicine, Pharmacology & Pharmaceutical medicine
          Keywords: Hirsutism, Late-onset congenital adrenal hyperplasia, ACTH test, 21-Hydroxylase deficiency, 17-Hydroxyprogesterone

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