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      Social functioning in patients with depressive and anxiety disorders

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          Abstract

          Objective

          Adaptive social functioning is severely impeded in depressive and anxiety disorders, even after remission. However, a comprehensive overview is still lacking.

          Method

          Using data from the Netherlands Study of Depression and Anxiety ( NESDA), behavioural (network size, social activities, social support) and affective (loneliness, affiliation, perceived social disability) indicators of social functioning were analyzed in patients with anxiety ( N = 540), depressive ( N = 393), comorbid anxiety and depressive disorders (‘comorbid’, N = 748), remitted participants ( N = 621), and healthy control subjects ( N = 650).

          Results

          Analyses revealed an increasing trend of social dysfunction among patient groups, in patients with comorbid anxiety and depressive disorders, showing the most severe impairments, followed by depressed and anxious patients ( P's < 0.001 for all social functioning indicators). Affective indicators showed the largest effect sizes (Cohen's d range from 0.13 to 1.76). We also found impairments in social functioning among remitted patients. Furthermore, perceived social disability among patients was predictive of still having a depressive and/or anxiety diagnosis 2 years later ( P < 0.01).

          Conclusions

          Behavioural but especially affective indicators of social functioning are impaired in patients with anxiety or depressive disorders and most in patients with comorbid disorders. After remission of affective psychopathology, residual impairments tend to remain, while social dysfunction in patients seems predictive of future psychopathology.

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          Most cited references40

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          The Inventory of Depressive Symptomatology (IDS): psychometric properties.

          The psychometric properties of the 28- and 30-item versions of the Inventory of Depressive Symptomatology, Clinician-Rated (IDS-C) and Self-Report (IDS-SR) are reported in a total of 434 (28-item) and 337 (30-item) adult out-patients with current major depressive disorder and 118 adult euthymic subjects (15 remitted depressed and 103 normal controls). Cronbach's alpha ranged from 0.92 to 0.94 for the total sample and from 0.76 to 0.82 for those with current depression. Item total correlations, as well as several tests of concurrent and discriminant validity are reported. Factor analysis revealed three dimensions (cognitive/mood, anxiety/arousal and vegetative) for each scale. Analysis of sensitivity to change in symptom severity in an open-label trial of fluoxetine (N = 58) showed that the IDS-C and IDS-SR were highly related to the 17-item Hamilton Rating Scale for Depression. Given the more complete item coverage, satisfactory psychometric properties, and high correlations with the above standard ratings, the 30-item IDS-C and IDS-SR can be used to evaluate depressive symptom severity. The availability of similar item content for clinician-rated and self-reported versions allows more direct evaluations of these two perspectives.
            • Record: found
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            • Article: not found
            Is Open Access

            Social functioning in major depressive disorder.

            Depression is associated with social risk factors, social impairments and poor social functioning. This paper gives an overview of these social aspects using the NIMH Research and Domain Criteria 'Systems for Social Processes' as a framework. In particular, it describes the bio-psycho-social interplay regarding impaired affiliation and attachment (social anhedonia, hyper-sensitivity to social rejection, competition avoidance, increased altruistic punishment), impaired social communication (impaired emotion recognition, diminished cooperativeness), impaired social perception (reduced empathy, theory-of-mind deficits) and their impact on social networks and the use of social media. It describes these dysfunctional social processes at the behavioural, neuroanatomical, neurochemical and genetic levels, and with respect to animal models of social stress. We discuss the diagnostic specificity of these social deficit constructs for depression and in relation to depression severity. Since social factors are importantly involved in the pathogenesis and the consequences of depression, such research will likely contribute to better diagnostic assessments and concepts, treatments and preventative strategies both at the diagnostic and transdiagnostic level.
              • Record: found
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              • Article: not found

              Quality of life in the anxiety disorders: a meta-analytic review.

              There has been significant interest in the impact of anxiety disorders on quality of life. In this meta-analytic review, we empirically evaluate differences in quality of life between patients with anxiety disorders and nonclinical controls. Thirty-two patient samples from 23 separate studies (N=2892) were included in the analysis. The results yielded a large effect size indicating poorer quality of life among anxiety disorder patients vs. controls and this effect was observed across all anxiety disorders. Compared to control samples, no anxiety disorder diagnosis was associated with significantly poorer overall quality of life than was any other anxiety disorder diagnosis. Examination of specific domains of QOL suggests that impairments may be particularly prominent among patients with post-traumatic stress disorder. QOL domains of mental health and social functioning were associated with the highest levels of impairment among anxiety disorder patients. These findings are discussed in the context of future research on the assessment of quality of life in the anxiety disorders.

                Author and article information

                Contributors
                i.saris@ggzingeest.nl , i.saris@vumc.nl
                Journal
                Acta Psychiatr Scand
                Acta Psychiatr Scand
                10.1111/(ISSN)1600-0447
                ACPS
                Acta Psychiatrica Scandinavica
                John Wiley and Sons Inc. (Hoboken )
                0001-690X
                1600-0447
                02 August 2017
                October 2017
                : 136
                : 4 ( doiID: 10.1111/acps.2017.136.issue-4 )
                : 352-361
                Affiliations
                [ 1 ] Department of Psychiatry Amsterdam Neuroscience and Amsterdam Public Health Research Institute VU University Medical Center and GGZ inGeest Amsterdam the Netherlands
                [ 2 ] Department of Psychiatry Leiden University Medical Center Leiden the Netherlands
                [ 3 ] Leiden Institute for Brain and Cognition Leiden the Netherlands
                Author notes
                [*] [* ] Ilja M. J. Saris, Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center and GGZ inGeest, AJ Ernststraat 1187, 1081 HL, Amsterdam, the Netherlands.

                E‐mails: i.saris@ 123456ggzingeest.nl ; i.saris@ 123456vumc.nl

                Author information
                http://orcid.org/0000-0003-3970-5123
                Article
                ACPS12774
                10.1111/acps.12774
                5601295
                28767127
                3aff8941-878a-4363-bd6a-129fdb95d088
                © 2017The Authors. Acta Psychiatrica Scandinavica Published by John Wiley & Sons Ltd

                This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

                History
                : 03 July 2017
                Page count
                Figures: 1, Tables: 4, Pages: 10, Words: 7521
                Funding
                Funded by: Geestkracht Programme of the Netherlands Organisation for Health Research and Development
                Award ID: 10‐000‐1002
                Funded by: EU‐PRISM Project
                Funded by: Innovative Medicines Initiative 2 Joint Undertaking
                Award ID: 115916
                Funded by: European Union's Horizon
                Categories
                Original Article
                Original Articles
                Custom metadata
                2.0
                acps12774
                October 2017
                Converter:WILEY_ML3GV2_TO_NLMPMC version:5.1.9 mode:remove_FC converted:18.09.2017

                Clinical Psychology & Psychiatry
                depression,anxiety,social functioning
                Clinical Psychology & Psychiatry
                depression, anxiety, social functioning

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